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96764 TGS1

96764

TGS1

trimethylguanosine synthase 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition trimethylguanosine synthase 1

研究结论

Date Results Publications
2021-03-20 13:23:00 Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation. 32023455
2016-10-22 12:17:00 Data highlight the importance of the catalytic activity of PIMT to mediate VEGF effects during endothelial cell migration and tube formation in angiogenesis. 26738492
2016-05-28 10:27:00 Self-association of Tgs1p and its catalytic activity were prerequisite to bypass the requirement for its accessory factor Swm2p for efficient pre-rRNA processing and snRNA trimethylation. 26074133
2014-05-03 11:33:00 PIMT was identified as a key player responsible for glycated low density lipoproteins induced vascular endothelial cell apoptosis. 23922881
2011-10-31 09:45:00 isoforms of the PIMT/Tgs1 protein with an RNA methyltransferase domain function both in the nucleus and in the cytoplasm 12943661

名称对应

Type IDs
Synonymous NCOA6IP, PIMT, PIPMT
Gene
UniProtKB-ID: TGS1_HUMAN
UniprotKB: Q96RS0
UniParc: UPI0000DBEF24
EMBL: AF286340, AY028423, BC011999, AY534911, AF432215, AC100817, AK026648
Ensembl: ENSG00000137574
KO: hsa:96764
Nucleutide sequences
EMBL-CDS: BAB15516.1, AAH11999.1, AAK27730.1, AAK83025.1, AAL99922.1, AAT02709.1
Ensembl_TRS: ENST00000260129
Protein sequencees
Ensembl_PRO: ENSP00000260129
RefSeq: NP_001350113.1, NP_079107.6, NP_001304831.1, XP_016869493.1, XP_006716548.1
Others
UniRef100: UniRef100_Q96RS0
UniRef90: UniRef90_Q96RS0
UniRef50: UniRef50_Q96RS0
UniGene: Hs.335068
CCDS: CCDS34894.1

全选

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研究热度

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