| Type | Description |
|---|---|
| Definition | TELO2 interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2014-05-31 11:48:00 | IP7, formed by IP6K2, binds CK2 to enhance its phosphorylation of the Tti1/Tel2 complex, thereby stabilizing DNA-PKcs and ATM. This process stimulates p53 phosphorylation at serine 15 to activate the cell death program. | 24657168 |
| 2010-12-05 22:08:00 | Observational study of gene-disease association. (HuGE Navigator) | 20800603 |
| 2010-09-20 11:27:00 | TTI1 and TTI2 protect cells from spontaneous DNA damage, and are required for the establishment of the intra-S and G2/M checkpoin | 20810650 |
| 2010-08-30 11:38:00 | Data show that that knockdown of either Tti1 or Tel2 causes disassembly of mTORC1 and mTORC2. | 20427287 |
| Type | IDs |
|---|---|
| Synonymous | KIAA0406, smg-10 |
| Gene |
UniProtKB-ID:
TTI1_HUMAN
UniprotKB:
O43156
UniParc:
UPI000012DB27
EMBL:
BR000854,
CH471077,
BC013121,
AL109823,
BC013755,
AB007866
Ensembl:
ENSG00000101407
KO:
hsa:9675
|
| Nucleutide sequences |
EMBL-CDS:
EAW76048.1,
FAA00688.1,
BAA23702.2,
AAH13755.1,
EAW76047.1,
AAH13121.1
Ensembl_TRS:
ENST00000449821,
ENST00000373448,
ENST00000373447
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362547,
ENSP00000362546,
ENSP00000407270
RefSeq:
NP_055472.1,
XP_016883637.1,
NP_001290386.1,
XP_011527416.1
|
| Others |
UniRef100:
UniRef100_O43156
UniRef90:
UniRef90_O43156
UniRef50:
UniRef50_O43156
UniGene:
Hs.655481
CCDS:
CCDS13300.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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