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9670 IPO13

9670

IPO13

importin 13

protein-coding

Homo sapiens

基因描述

Type Description
Definition importin 13

研究结论

Date Results Publications
2020-04-25 12:14:00 This study reports the identification of mutation (c.331C>T, p.R111C) in the IPO13 gene in a consanguineous family with ocular coloboma, microphthalmia, and cataract by a combination of whole-exome sequencing and homozygosity mapping. 29700284
2019-05-04 11:49:00 this study significantly expands the repertoire of importin 13 cargoes and sets the basis for a more detailed characterization of this extremely versatile transport receptor. 29666159
2019-04-06 11:40:00 This is the first report that IPO13 can be phosphorylated at Ser193 and that this modification regulates IPO13 subcellular localization and nucleocytoplasmic transport function, with important implications for IPO13's role in development and other processes. 30045875
2019-03-30 11:18:00 The anti- glucocorticoid receptor effect of respiratory syncytial virus was mediated by viral nonstructural protein 1, which likely functioned by competing with IPO13 for glucocorticoid receptor binding. 28968829
2014-02-01 10:42:00 IPO13 influenced intracellular distribution of CTCF. 23620300

名称对应

Type IDs
Synonymous IMP13, KAP13, LGL2, RANBP13
Gene
UniProtKB-ID: IPO13_HUMAN
UniprotKB: O94829
UniParc: UPI0000073F11
EMBL: AB018267, AF267987, AL117501, BC008194, CH471059, AL357079, AK023441
Ensembl: ENSG00000117408
KO: hsa:9670
Nucleutide sequences
EMBL-CDS: AAF73471.1, CAB55966.1, BAA34444.2, AAH08194.1, BAB14575.1, EAX07073.1, EAX07072.1
Ensembl_TRS: ENST00000372343
Protein sequencees
Ensembl_PRO: ENSP00000361418
RefSeq: XP_024306838.1, NP_055467.3, XP_024306837.1
Others
UniRef100: UniRef100_O94829
UniRef90: UniRef90_O94829
UniRef50: UniRef50_O94829
UniGene: Hs.158497
CCDS: CCDS503.1

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