| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 5B |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 12:45:00 | Data suggest that eIF5B represents a regulatory node, allowing cancer cells to evade apoptosis by promoting the translation of pro-survival proteins from IRES-containing mRNAs. | 30670698 |
| 2019-07-20 10:57:00 | results indicate that in humans, eIF5B displacing eIF2 from upon subunit joining may be coupled to eIF1A displacing eIF5 from eIF5B, allowing the eIF5:eIF2-GDP complex to leave the ribosome. | 30211544 |
| 2019-03-30 10:23:00 | aerobic eukarya retained eIF5B/IF2 to remodel anaerobic pathways during episodes of oxygen deficiency. | 29298419 |
| 2018-02-10 11:46:00 | eIF5B promoted hepatocellular carcinoma cell proliferation and migration in vitro and in vivo partly through increasing ASAP1 expression. | 27694689 |
| 2017-07-15 11:25:00 | eIF5B silencing provides a negative feedback to deactivate MAPK signaling | 27959964 |
| Type | IDs |
|---|---|
| Synonymous | IF2 |
| Gene |
UniProtKB-ID:
IF2P_HUMAN,
Q8N5A0_HUMAN
UniprotKB:
O60841,
Q8N5A0
UniParc:
UPI0000207EC7,
UPI000006F32F
EMBL:
AJ006412,
AF078035,
AJ006776,
AC079447,
AC018690,
BC032639,
AL133563,
AB018284
Ensembl:
ENSG00000158417
KO:
hsa:9669
|
| Nucleutide sequences |
EMBL-CDS:
AAD16006.1,
CAB44357.1,
AAY24313.1,
CAB63717.1,
CAA07018.1,
AAX93258.1,
BAA34461.2,
AAH32639.1
Ensembl_TRS:
ENST00000289371
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000289371
RefSeq:
NP_056988.3
|
| Others |
UniRef100:
UniRef100_O60841,
UniRef100_Q8N5A0
UniRef90:
UniRef90_O60841
UniRef50:
UniRef50_O60841
UniGene:
Hs.158688
CCDS:
CCDS42721.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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