| Type | Description |
|---|---|
| Definition | inhibitor of nuclear factor kappa B kinase subunit epsilon |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:28:00 | IKBKE enhances TMZ-chemoresistance through upregulation of MGMT expression in glioblastoma. | 31865606 |
| 2021-03-20 13:29:00 | The breast cancer oncogene IKKepsilon coordinates mitochondrial function and serine metabolism. | 32783398 |
| 2020-09-19 16:26:00 | Zika Virus NS5 Inhibits the RIG-I Pathway and Interferon Lambda 1 Promoter Activation by Targeting IKK Epsilon. | 31690057 |
| 2020-08-22 15:26:00 | IKBKE activity enhances AR levels in advanced prostate cancer via modulation of the Hippo pathway. | 32324216 |
| 2020-07-25 11:55:00 | Results demonstrate that PDCoV NS7a inhibits IFN-beta production by disrupting the association of IKKepsilon with both TRAF3 and IRF3, revealing a new mechanism utilized by a PDCoV accessory protein to evade the host antiviral innate immune response. | 32656094 |
| Type | IDs |
|---|---|
| Synonymous | IKK-E, IKK-i, IKKE, IKKI |
| Gene |
UniProtKB-ID:
IKKE_HUMAN,
A0A075B7B4_HUMAN
UniprotKB:
Q14164,
A0A075B7B4
UniParc:
UPI0000E060E6,
UPI00005D3A5D,
UPI0000033727
EMBL:
AF241789,
AC244034,
AL354681,
D63485,
DQ667176,
CH471100,
BC107812,
BC105924,
BC105923,
AB016590
Ensembl:
ENSG00000263528
KO:
hsa:9641
|
| Nucleutide sequences |
EMBL-CDS:
AAF45307.1,
EAW93549.1,
ABG25921.1,
BAA85155.1,
AAI07813.1,
BAA09772.2,
AAI05925.1,
CAI15250.1,
AAI05924.1
Ensembl_TRS:
ENST00000581977,
ENST00000584998,
ENST00000578328
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000464030,
ENSP00000462396,
ENSP00000473833
RefSeq:
XP_005273413.1,
XP_016858357.1,
NP_001180250.1,
NP_054721.1,
NP_001180251.1
|
| Others |
UniRef100:
UniRef100_Q14164,
UniRef100_A0A075B7B4
UniRef90:
UniRef90_Q14164,
UniRef90_G3RVG0
UniRef50:
UniRef50_Q14164
UniGene:
Hs.321045
CCDS:
CCDS53464.1,
CCDS30996.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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