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9631 NUP155

9631

NUP155

nucleoporin 155

protein-coding

Homo sapiens

基因描述

Type Description
Definition nucleoporin 155

研究结论

Date Results Publications
2020-03-28 10:13:00 lamin A/C mutation p.Arg399Cys weakens the interaction between nuclear lamina (lamin A/C) and the nuclear pore complex (NUP155), leading to the development of atrial fibrillation. 30488537
2019-07-06 12:50:00 Study revealed that NUP155 controls mRNA translation CDKN1A, a key mediator of the p53 response. 31089132
2011-06-18 10:35:00 The Nup155-mediated localization was required for HDAC4's effect on gene expression. 21464227
2010-12-11 10:23:00 The Nup155 depletion massively alters nuclear envelope structure, causing a dramatic decrease in Nuclear pore complexes numbers and the improper targeting of membrane proteins to the inner nuclear membrane. 20974814
2010-01-21 00:00:00 These human and mouse studies indicate that loss of NUP155 function causes atrial fibrillation by altering mRNA and protein transport and link the nuclear pore complex to cardiovascular disease. 19070573

名称对应

Type IDs
Synonymous ATFB15, N155
Gene
UniProtKB-ID: NU155_HUMAN, E9PF10_HUMAN, B4DLT2_HUMAN, A0A024R071_HUMAN
UniprotKB: O75694, E9PF10, B4DLT2, A0A024R071
UniParc: UPI0000001C7F, UPI000013F242, UPI0001D3B217, UPI00017A7381
EMBL: AB018334, AJ007558, AC117532, BC039257, AF165926, AC025449, AC008832, CH471119, AL117585, AK297143
Ensembl: ENSG00000113569
KO: hsa:9631
Nucleutide sequences
EMBL-CDS: AAD52966.1, CAB56007.1, CAA07553.1, BAA34511.2, AAH39257.1, BAG59644.1, EAW55957.1, EAW55958.1
Gene_ORFName: hCG_37558
Ensembl_TRS: ENST00000231498, ENST00000381843, ENST00000513532
Protein sequencees
Ensembl_PRO: ENSP00000371265, ENSP00000231498, ENSP00000422019
RefSeq: NP_705618.1, NP_001265241.1, NP_004289.1, XP_011512467.1
Others
UniRef100: UniRef100_O75694, UniRef100_E9PF10
UniRef90: UniRef90_E9PF10, UniRef90_O75694
UniRef50: UniRef50_O75694
UniGene: Hs.547696
CCDS: CCDS43310.1, CCDS3921.1

全选

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