| Type | Description |
|---|---|
| Definition | synuclein alpha interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2019-03-16 10:59:00 | results indicated that synphilin-1 may play neuroprotective roles in Parkinson Disease pathogenesis by inhibiting production and apoptosis. | 30316984 |
| 2016-04-30 11:30:00 | Differential expression of synphilin-1 isoforms (and alpha-synuclein and parkin) was found in multiple system atrophy brains compared to control brain. | 26465922 |
| 2015-09-05 10:48:00 | Synphilin-1 binds ATP, but not CTP. | 25545246 |
| 2015-01-03 11:42:00 | Overexpression of human synphilin-1 in mice resulted in hyperphagia and obesity. | 24829096 |
| 2013-05-18 11:02:00 | Overexpression of SP1 in neurons, but not peripheral cells, increased the body weight of flies compared with that of non-transgenic controls. SP1 increased food intake but did not affect locomotor activity | 22828940 |
| Type | IDs |
|---|---|
| Synonymous | SYPH1, Sph1 |
| Gene |
UniProtKB-ID:
SNCAP_HUMAN,
Q6L981_HUMAN,
B7Z616_HUMAN,
B7Z995_HUMAN,
Q6L983_HUMAN
UniprotKB:
Q9Y6H5,
Q6L981,
B7Z616,
B7Z995,
Q6L983
UniParc:
UPI000006D872,
UPI0000D5B9CB,
UPI0000413E95,
UPI0001914FAF,
UPI000023272B,
UPI0000375B68,
UPI0001638BE6,
UPI0000375B67,
UPI0000423143,
UPI0000375B6A
EMBL:
AF167304,
AF167302,
AB110793,
AC022101,
DQ227317,
AB110791,
BC040552,
AK299687,
AB110789,
AC119150,
BC033743,
AF167305,
AF167303,
AC113349,
AB110790,
AF167306,
AB110788,
BC094759,
AK304646,
CH471086,
AF076929,
AF167301,
KF457986
Ensembl:
ENSG00000064692
KO:
hsa:9627
|
| Nucleutide sequences |
EMBL-CDS:
EAW48890.1,
BAD19019.1,
AAG17478.1,
BAD19018.1,
AAD30362.1,
BAD19017.1,
AAH40552.1,
AAH94759.1,
ABB51162.1,
EAW48889.1,
AAH33743.1,
BAD19022.1,
BAH13102.1,
BAH14231.1,
BAD19020.1
Ensembl_TRS:
ENST00000261368,
ENST00000395469,
ENST00000261367,
ENST00000379538,
ENST00000395466,
ENST00000512146,
ENST00000542191
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261367,
ENSP00000368854,
ENSP00000261368,
ENSP00000378852,
ENSP00000378849,
ENSP00000423360,
ENSP00000441681
RefSeq:
XP_016865572.1,
XP_016865569.1,
XP_011542040.1,
XP_024302037.1,
XP_011542051.1,
XP_011542041.1,
NP_005451.2,
NP_001295034.1,
NP_001295035.1,
XP_024302034.1,
XP_016865570.1,
XP_016865575.1,
NP_001295036.1,
XP_016865574.1,
XP_016865567.1,
XP_005272195.1,
XP_016865573.1,
XP_005272196.1,
XP_011542043.1,
XP_024302035.1,
NP_001229864.1,
XP_011542052.1,
XP_006714797.1,
NP_001295037.1,
XP_011542039.1,
XP_011542045.1,
NP_001295029.1,
XP_024302036.1,
XP_016865571.1,
XP_011542047.1,
XP_016865568.1,
NP_001295038.1
|
| Others |
UniRef100:
UniRef100_Q6L981,
UniRef100_B7Z995,
UniRef100_B7Z616,
UniRef100_Q9Y6H5,
UniRef100_Q6L983
UniRef90:
UniRef90_Q6L981,
UniRef90_A0A2J8LK77,
UniRef90_Q9Y6H5,
UniRef90_A0A2I3GDI6
UniRef50:
UniRef50_A0A2J8LK77,
UniRef50_A0A5F4C121,
UniRef50_A0A2I3GDI6,
UniRef50_Q9Y6H5
UniGene:
Hs.426463
CCDS:
CCDS4131.1,
CCDS58964.1,
CCDS78054.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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