| Type | Description |
|---|---|
| Definition | ring finger protein 7 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-10 11:35:00 | We demonstrated that RNF7 knockdown induced growth suppression of prostate cancer cells and inactivated ERK1/2 pathway, which suggested RNF7 might be a potential novel therapeutic target for CRPC. | 28252001 |
| 2018-07-14 11:17:00 | Results identified RNF7 to interact with CARMA2 regulating its NF-kappaB-activating capacity. Mechanistically, RNF7 influences CARMA2 signaling by regulating the ubiquitination state of MALT1 and the NF-kappaB-regulatory molecule NEMO. | 29194363 |
| 2018-06-09 11:04:00 | This is the first report on a diagnostic test for simultaneous genotyping of IFNL3, ABCB11, and RNF7 in Chronic hepatitis C (CHC) patients. Reliable and inexpensive, the assay should provide useful information for the clinical management of CHC, like identification of patients at risk of rapid disease progression or with high chances of response to classic therapy. | 28860020 |
| 2018-05-31 16:00:00 | Sag is a Kras-cooperating oncogene that promotes lung tumorigenesis | 24430184 |
| 2018-05-31 15:57:00 | NEDD4-1 overexpression sensitizes cancer cells to etoposide-induced apoptosis by reducing SAG levels through targeted degradation. SAG is added to a growing list of NEDD4-1 substrates and mediates its biological function. | 25216516 |
| Type | IDs |
|---|---|
| Synonymous | CKBBP1, ROC2, SAG, rbx2 |
| Gene |
UniProtKB-ID:
RBX2_HUMAN
UniprotKB:
Q9UBF6
UniParc:
UPI000006DC4E,
UPI000015C5A3,
UPI000006EC30,
UPI000015C5A2
EMBL:
AF312226,
BC005966,
AF092878,
AK289894,
DB272382,
AC112771,
CH471052,
BT007348,
AF164679,
BC008627,
AF142060
Ensembl:
ENSG00000114125
KO:
hsa:9616
|
| Nucleutide sequences |
EMBL-CDS:
AAD55984.1,
EAW78992.1,
AAD30147.1,
AAH08627.1,
EAW78991.1,
EAW78996.1,
AAK37450.1,
EAW78994.1,
BAF82583.1,
AAD25962.1,
EAW78995.1,
AAP36012.1,
AAH05966.1
Ensembl_TRS:
ENST00000477012,
ENST00000273480,
ENST00000480908,
ENST00000393000
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000419084,
ENSP00000376725,
ENSP00000419339,
ENSP00000273480
RefSeq:
NP_001188299.1,
NP_899060.1,
NP_055060.1
|
| Others |
UniRef100:
UniRef100_Q9UBF6
UniRef90:
UniRef90_Q9UBF6
UniRef50:
UniRef50_Q9UBF6
UniGene:
Hs.134623
CCDS:
CCDS3118.1,
CCDS43158.1,
CCDS56283.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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