| Type | Description |
|---|---|
| Definition | phosphatidylinositol transfer protein membrane associated 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 11:03:00 | Authors found that the phosphatidylinositol transfer protein Nir2 acts as an LTP and may replenish PI at the HCV RO by interacting with VAMP-associated proteins (VAPs), enabling continuous viral replication during chronic infection. | 31484747 |
| 2015-09-05 11:38:00 | results suggest that Nir2 not only enhances EMT in vitro and breast cancer metastasis in animal models, but also contributes to breast cancer progression in human patients. | 25179602 |
| 2015-08-29 11:15:00 | Phosphatidic acid production triggers Phosphatidylinositol 4,5-Bisphosphate replenishment mediated by Nir2 and Nir3 at endoplasmic reticulum-plasma membrane junctions. | 25887399 |
| 2014-11-08 12:20:00 | Nir2 translocates from the Golgi complex to the plasma membrane in response to GF stimulation. | 23897088 |
| 2014-08-30 12:03:00 | Results suggest a feedback mechanism that replenishes PM PIP2 during receptor-induced Ca(2+) signaling via the Ca(2+) effector E-Syt1 and the PITP Nir2 at ER-PM junctions. | 24183667 |
| Type | IDs |
|---|---|
| Synonymous | DRES9, NIR2, PITPNM, RDGB, RDGB1, RDGBA, RDGBA1, Rd9 |
| Gene |
UniProtKB-ID:
PITM1_HUMAN,
B2R787_HUMAN,
A0A024R5I7_HUMAN
UniprotKB:
O00562,
B2R787,
A0A024R5I7
UniParc:
UPI00001FAD31,
UPI000006E253,
UPI000175050E
EMBL:
AK312886,
AY429102,
CH471076,
BC022230,
AF334584,
X98654,
AP001184
Ensembl:
ENSG00000110697
KO:
hsa:9600
|
| Nucleutide sequences |
EMBL-CDS:
AAK01444.1,
AAR06909.1,
CAA67224.1,
EAW74638.1,
AAH22230.1,
BAG35734.1,
EAW74641.1,
EAW74643.1
Gene_ORFName:
hCG_21051
Ensembl_TRS:
ENST00000356404,
ENST00000534749,
ENST00000436757
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000348772,
ENSP00000437286,
ENSP00000398787
RefSeq:
NP_004901.2,
NP_001124320.1,
XP_016874075.1,
XP_011543698.1
|
| Others |
UniRef100:
UniRef100_B2R787,
UniRef100_O00562
UniRef90:
UniRef90_Q5U2N3,
UniRef90_O00562
UniRef50:
UniRef50_Q5U2N3,
UniRef50_O00562
UniGene:
Hs.372295
CCDS:
CCDS31620.1,
CCDS44659.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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