| Type | Description |
|---|---|
| Definition | cytohesin 1 interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2014-10-25 11:25:00 | CASP has a direct role in the secretion of IFN-gamma, and NK cell motility and ability to kill tumor cells. CASP polarizes to the leading edge of migrating NK cells, and to the immunological synapse when engaged with tumor cells. | 25058460 |
| 2013-09-14 12:12:00 | a newly identified binding partner of CYTIP, SOCS-1, and confirm its function in regulating the degradation of CYTIP by the proteasome | 23469018 |
| 2013-03-09 10:08:00 | loss of DNA methylation enables HIF-driven cytohesin 1 interacting protein expression to protect cancer cells from death cytokine signals | 23223005 |
| 2011-09-03 11:39:00 | on infection of human monocyte-derived dendritic cells with herpes simplex virus type 1 (HSV-1), CYTIP is rapidly degraded and as a consequence beta-2 integrins, predominantly LFA-1, are activated | 21562043 |
| 2010-06-30 22:05:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| Type | IDs |
|---|---|
| Synonymous | B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP |
| Gene |
UniProtKB-ID:
CYTIP_HUMAN
UniprotKB:
O60759
UniParc:
UPI00017A805F,
UPI0000035D67
EMBL:
AK301544,
BC036449,
AF068836,
AC019201,
L06633
Ensembl:
ENSG00000115165
KO:
hsa:9595
|
| Nucleutide sequences |
EMBL-CDS:
AAY14898.1,
BAG63041.1,
AAA16575.1,
AAH36449.1,
AAC19129.1
Ensembl_TRS:
ENST00000264192
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000264192
RefSeq:
NP_004279.3,
XP_016860875.1
|
| Others |
UniRef100:
UniRef100_O60759
UniRef90:
UniRef90_O60759
UniRef50:
UniRef50_O60759
UniGene:
Hs.270
CCDS:
CCDS2204.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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