| Type | Description |
|---|---|
| Definition | immediate early response 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:02:00 | Immediate early response protein 2 promotes the migration and invasion of hepatocellular carcinoma cells via regulating the activity of Rho GTPases. | 32009420 |
| 2020-04-11 11:05:00 | The results suggest that IER2, IER5, and IER5L proteins are target protein-specific regulators of PP2A (protein phosphatase 2A) activity and modulate cell proliferation through CDC25A (cell division cycle 25A protein) activity. | 30599213 |
| 2017-03-25 11:54:00 | IER2 promoted hepatocellular carcinoma cell adhesion and motility by directly increasing ITGB1 expression and subsequently activating the ITGB1FAKSrcpaxillin signal pathway. | 27840969 |
| 2016-06-28 10:57:00 | results from western blot analysis showed that the activity of the focal adhesion kinase (FAK) can be regulated by IER2. | 26260137 |
| 2012-11-03 11:50:00 | ectopic Ier2 expression promoted the motility and invasiveness of poorly metastatic 1AS pancreatic tumor cells in vitro | 22120713 |
| Type | IDs |
|---|---|
| Synonymous | ETR101 |
| Gene |
UniProtKB-ID:
IER2_HUMAN,
A0A024R7H1_HUMAN
UniprotKB:
Q9BTL4,
A0A024R7H1
UniParc:
UPI000006D032
EMBL:
CH471106,
CR450352,
BT019466,
BC003625,
BC110647,
M62831,
BC072432
Ensembl:
ENSG00000160888
KO:
hsa:9592
|
| Nucleutide sequences |
EMBL-CDS:
AAV38273.1,
AAI10648.1,
AAA35814.1,
CAG29348.1,
AAH72432.1,
AAH03625.1,
EAW84360.1,
EAW84359.1,
EAW84358.1
Gene_ORFName:
hCG_26671
Ensembl_TRS:
ENST00000587885,
ENST00000588173,
ENST00000292433
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000467294,
ENSP00000292433,
ENSP00000465617
RefSeq:
NP_004898.2
|
| Others |
UniRef100:
UniRef100_Q9BTL4
UniRef90:
UniRef90_Q9BTL4
UniRef50:
UniRef50_Q9BTL4
UniGene:
Hs.501629
CCDS:
CCDS12295.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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