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9584 RBM39

9584

RBM39

RNA binding motif protein 39

protein-coding

Homo sapiens

基因描述

Type Description
Definition RNA binding motif protein 39

研究结论

Date Results Publications
2020-05-02 12:38:00 The splicing factors U2AF65 and CAPERalpha engage multivalent interactions through their low complexity RS domains. The resulting assemblies can bridge the U2snRNP component SF3b155 with repeated polypyrimidine tracts in introns, to promote alternative splicing. 31271494
2020-04-25 12:42:00 aryl-sulfonamides neo-functionalize a shallow, non-conserved pocket on DCAF15 to selectively bind and degrade RBM39 and the closely related splicing factor RBM23 without the requirement for a high-affinity ligand 31686031
2020-04-25 12:29:00 structural and mutational analysis of how indisulam mediates the DCAF15-RBM39 interaction 31819272
2017-12-16 11:36:00 Decreased expression of CAPERalpha appears to be correlated with appearance of microvessels in hepatocellular carcinoma 26934653
2017-11-04 11:37:00 RBM39 is extensively involved in alternative splicing of RNA and helps regulate transcript levels. RBM39 may modulate alternative splicing similarly to U2AF65 by either directly binding to RNA or recruiting other splicing factors, such as U2AF65. 27354116

名称对应

Type IDs
Synonymous CAPER, CAPERalpha, FSAP59, HCC1, RNPC2
Gene
UniProtKB-ID: RBM39_HUMAN, B4DRA0_HUMAN, E1P5S2_HUMAN, Q6N037_HUMAN, A0A384NQ03_HUMAN
UniprotKB: Q14498, B4DRA0, E1P5S2, Q6N037, A0A384NQ03
UniParc: UPI0000134418, UPI00005BE04B, UPI000002B291, UPI000016CA6C, UPI00001D2D33, UPI00017A7B0E
EMBL: AL357374, CH471077, BC131543, AK299165, L10910, BX640714, GQ900961, L10911, BC141835, AK299678, BC158172
Ensembl: ENSG00000131051
KO: hsa:9584
Nucleutide sequences
EMBL-CDS: EAW76161.1, EAW76162.1, BAG61586.1, AAA16347.1, AAI58173.1, AAI41836.1, AAI31544.1, EAW76159.1, EAW76163.1, AAA16346.1, BAG61212.1, EAW76165.1, EAW76160.1, EAW76164.1, CAE45833.1, ADO22478.1
Gene_ORFName: hCG_38221, hCG_38221
Ensembl_TRS: ENST00000253363, ENST00000528062, ENST00000361162
Protein sequencees
Ensembl_PRO: ENSP00000354437, ENSP00000436747, ENSP00000253363
RefSeq: XP_016883635.1, XP_011527413.1, NP_001310351.1, XP_016883630.1, NP_001229529.1, NP_001310352.1, XP_016883632.1, XP_016883627.1, XP_016883636.1, XP_024307792.1, NP_001310353.1, XP_006723953.1, XP_006723954.1, XP_024307791.1, XP_024307790.1, NP_909122.1, XP_016883633.1, XP_016883634.1, XP_016883631.1, NP_004893.1, XP_016883628.1, XP_024307793.1, NP_001229528.1, XP_016883629.1
Others
UniRef100: UniRef100_B4DRA0, UniRef100_E1P5S2, UniRef100_Q5RC80, UniRef100_Q14498
UniRef90: UniRef90_K7GIU3, UniRef90_Q14498, UniRef90_Q5RC80
UniRef50: UniRef50_Q14498, UniRef50_Q5RC80
UniGene: Hs.282901
CCDS: CCDS13265.1, CCDS13266.1, CCDS56186.1

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