| Type | Description |
|---|---|
| Definition | growth differentiation factor 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-29 10:27:00 | the 4 of the 5 variants in [i]GDF3[/i] gene contribute different pathogenicity in congenital scoliosis, which may provide molecular evidence for clinical genetic testing. | 29735971 |
| 2017-01-28 10:23:00 | OCT4 plays a role as a transcriptional activator for GDF3 transcription in pluripotent human embryonic carcinoma NCCIT cells and contributes to the understanding of the molecular networks of stem cell regulators in germ cell-derived pluripotency and tumorigenesis. | 27803451 |
| 2016-06-04 10:54:00 | The results expand the spectrum of mutations associated with CHDs and first suggest the potentially disease-related GDF3 gene variant in the pathogenesis of CHDs. | 25372014 |
| 2012-12-08 10:02:00 | first evidence that NANOG is a transcriptional activator of the expression of the oncogenic growth factor GDF3 in embryonic carcinoma cells | 22963770 |
| 2012-09-15 10:17:00 | GDF3 expression level was significantly down-regulated in breast cancer tissues compared to the surrounding nontumorous tissues. | 22488170 |
| Type | IDs |
|---|---|
| Synonymous | KFS3, MCOP7, MCOPCB6 |
| Gene |
UniProtKB-ID:
GDF3_HUMAN
UniprotKB:
Q9NR23
UniParc:
UPI0000049E0E
EMBL:
AY358875,
AF263538,
BC030959,
AC006927
Ensembl:
ENSG00000184344
KO:
hsa:9573
|
| Nucleutide sequences |
EMBL-CDS:
AAQ89234.1,
AAF91389.1,
AAH30959.1
Gene_ORFName:
UNQ222/PRO248
Ensembl_TRS:
ENST00000329913
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000331745
RefSeq:
NP_065685.1
|
| Others |
UniRef100:
UniRef100_Q9NR23
UniRef90:
UniRef90_Q9NR23
UniRef50:
UniRef50_Q9NR23
UniGene:
Hs.86232
CCDS:
CCDS8581.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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