| Type | Description |
|---|---|
| Definition | GTF2I repeat domain containing 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:33:00 | GTF2IRD1 overexpression promotes tumor progression and correlates with less CD8+ T cells infiltration in pancreatic cancer. | 32936232 |
| 2020-02-22 10:37:00 | Study showed that GTF2IRD1 was overexpressed due to copy number amplification at Ch.7q in colorectal cancer (CRC). The expression of GTF2IRD1 was positively associated with the malignant pathological phenotype. Furthermore, high expression of GTF2IRD1 was an independent poor prognostic factor in CRC. Mechanistically, GTF2IRD1 promoted cell cycle progression by downregulation of TGFbetaR2 in CRC. | 31758608 |
| 2019-02-09 12:40:00 | Among 110 SNPs within the 7q11.23 William's Syndrome (WS) chromosomal region, we found one associated locus located at GTF2IRD1, which has been implicated in animal models of WS. | 29884845 |
| 2017-09-23 10:11:00 | The mis-regulation of genes downstream of GTF2IRD1, including TbetaR2 and BMPR1b, also individually promoted mammary cancer development, and silencing of TbetaR2 suppressed GTF2IRD1-driven tumor promotion. | 27239038 |
| 2015-12-19 10:23:00 | Study demonstrates a significant association between SLE in Chinese Han population and the GTF2I rs117026326 T allele/GTF2IRD1 rs4717901 C allele. | 26320362 |
| Type | IDs |
|---|---|
| Synonymous | BEN, CREAM1, GTF3, MUSTRD1, RBAP2, WBS, WBSCR11, WBSCR12, hMusTRD1alpha1 |
| Gene |
UniProtKB-ID:
GT2D1_HUMAN,
E9PFE2_HUMAN
UniprotKB:
Q9UHL9,
E9PFE2
UniParc:
UPI0001639641,
UPI00003BF92B,
UPI000012AE30,
UPI000002AA1E
EMBL:
AF089107,
AF156489,
AC004851,
KF495976,
AC211433,
BC018136,
AY648295,
AF151354,
AF118270,
AF104923,
AC005231,
AC005015
Ensembl:
ENSG00000006704
KO:
hsa:9569
|
| Nucleutide sequences |
EMBL-CDS:
AAP21877.1,
AAT68469.1,
AAF17358.1,
AAF21796.1,
AAD27668.1,
AAF19786.1,
AAS00362.1,
AAD14687.2,
AAH18136.1
Ensembl_TRS:
ENST00000424337,
ENST00000455841,
ENST00000265755,
ENST00000476977
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000265755,
ENSP00000408477,
ENSP00000397566,
ENSP00000418383
RefSeq:
NP_005676.3,
XP_006716245.1,
XP_006716246.1,
XP_016868293.1,
NP_057412.1,
XP_016868294.1,
XP_011515015.1,
XP_016868291.1,
XP_016868292.1,
NP_001186136.1
|
| Others |
UniRef100:
UniRef100_E9PFE2,
UniRef100_Q9UHL9
UniRef90:
UniRef90_Q9UHL9
UniRef50:
UniRef50_Q9UHL9
UniGene:
Hs.647056
CCDS:
CCDS56492.1,
CCDS5571.1,
CCDS47613.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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