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956530 NA

956530

NA

neuraminidase

protein-coding

Influenza A virus (A/Puerto Rico/8/1934(H1N1))

基因描述

Type Description
Definition neuraminidase

研究结论

Date Results Publications
2021-02-27 13:46:00 Cross protection by inactivated recombinant influenza viruses containing chimeric hemagglutinin conjugates with a conserved neuraminidase or M2 ectodomain epitope. 32882637
2019-05-11 11:04:00 substitutions in HA (Asp225Gly or Gln226Arg) and compensatory mutation decreasing the charge of HA (Lys123Asn, Lys157Asn, Gly158Glu, Asn159Asp, or Lys212Met) altered viral receptor-binding specificity and restored the functional balance between HA and NA; (2) Phe35Leu substitution in the PA protein increased viral polymerase activity. 30113030
2016-04-23 11:21:00 we also demonstrate that NA[neuraminidase] mutations at residue Q136 can confer reduced zanamivir, peramivir or laninamivir susceptibility. 26608955
2015-11-07 10:39:00 FLUAV strains can counteract tetherin via their HA and NA proteins identifies these proteins as novel tetherin antagonists and indicates that HA/NA-dependent inactivation of innate defenses may contribute to the efficient spread of pandemic FLUAV. 26109730
2015-09-05 11:38:00 study found six mutations in NA genes of five independent dextran sulfate resistant viruses and each resistant NA gene had two mutations; all mutations were from basic to acidic or neutral amino acids 25234090

名称对应

Type IDs
Gene
UniProtKB-ID: NRAM_I34A1
UniprotKB: P03468
UniParc: UPI0000F23D12
EMBL: AF389120, K01031, EF467823, J02146, CY009446
KO: vg:956530
Nucleutide sequences
EMBL-CDS: ABO21711.1, ABD77678.1, AAA43415.1, AAM75160.1, AAA43412.1
Protein sequencees
RefSeq: NP_040981.1
Others
UniRef100: UniRef100_P03468
UniRef90: UniRef90_P03468
UniRef50: UniRef50_P03468

全选

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