| Type | Description |
|---|---|
| Definition | BCAR1 scaffold protein, Cas family member |
| Date | Results | Publications |
|---|---|---|
| 2020-02-08 12:17:00 | p130Cas (BCAR1) is recruited to filopodia tips via its C-terminal Cas family homology domain (CCHD) and acts as a mechanosensitive regulator of filopodia stability. | 30639111 |
| 2019-12-21 10:55:00 | a novel interaction of p130Cas with Ser/Thr kinase PKN3, is reported. | 30422386 |
| 2019-05-04 10:05:00 | a feedforward autocrine loop to promote invasion through a FAK>p130Cas>c-Jun>MMP-9 signaling axis. | 30531837 |
| 2018-12-22 12:33:00 | study showed that RBMS1 gene rs7593730 and BCAR1 gene rs7202877 were significantly associated with type 2 diabetes in the Chinese population | 30188962 |
| 2018-11-17 10:35:00 | These results suggest that miR-24-3p functions as a tumor suppressor and the miR-24-3p/p130Cas axis is a novel factor of cancer progression by regulating cell migration and invasion. | 28337997 |
| Type | IDs |
|---|---|
| Synonymous | CAS, CAS1, CASS1, CRKAS, P130Cas |
| Gene |
UniProtKB-ID:
BCAR1_HUMAN,
B3KWE2_HUMAN
UniprotKB:
P56945,
B3KWE2
UniParc:
UPI0001AE689B,
UPI00017A72B7,
UPI0000409D8B,
UPI00001FFC19,
UPI00001FFC1D,
UPI00001FFC1B,
UPI0000409D8E,
UPI0001C0B383,
UPI0001C0B382
EMBL:
AK124815,
AY545071,
AC009078,
AK294513,
AK124844,
AK293808,
AF218451,
AB040024,
AK302617,
AJ242987,
AK027608,
AK295809
Ensembl:
ENSG00000050820
KO:
hsa:9564
|
| Nucleutide sequences |
EMBL-CDS:
BAG58627.1,
BAG57726.1,
CAB75875.2,
BAH13763.1,
BAA92711.1,
AAS48631.1,
BAG57215.1,
BAB55230.1,
AAF27527.1,
BAG54099.1,
BAG54104.1
Ensembl_TRS:
ENST00000420641,
ENST00000393420,
ENST00000535626,
ENST00000393422,
ENST00000162330,
ENST00000418647,
ENST00000542031,
ENST00000538440
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000162330,
ENSP00000377074,
ENSP00000443841,
ENSP00000392708,
ENSP00000440370,
ENSP00000440415,
ENSP00000391669,
ENSP00000377072
RefSeq:
NP_001164191.1,
NP_001164190.1,
NP_001164185.1,
NP_001164187.1,
NP_001164192.1,
NP_055382.2,
NP_001164188.1,
NP_001164189.1,
NP_001164186.1
|
| Others |
UniRef100:
UniRef100_P56945,
UniRef100_B3KWE2
UniRef90:
UniRef90_P56945-4,
UniRef90_P56945
UniRef50:
UniRef50_P56945-4,
UniRef50_P56945
UniGene:
Hs.479747
CCDS:
CCDS54042.1,
CCDS10915.1,
CCDS54040.1,
CCDS54038.1,
CCDS54039.1,
CCDS54037.1,
CCDS54043.1,
CCDS54041.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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