| Type | Description |
|---|---|
| Definition | hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase |
| Date | Results | Publications |
|---|---|---|
| 2019-01-05 11:37:00 | Knockdown of H6PD resulted in an increase in ER lumen oxidation, and down-regulation of many components of the unfolded protein response, including the transcription factors activating transcription factor-4, activating transcription factor-6, split X-box binding protein-1, and CCAAT/enhancer binding protein homologous protein. | 29295867 |
| 2017-09-23 12:28:00 | Data indicate the tetramer as the most active form of glucose-6-phosphate dehydrogenase (G6PDH). | 28370139 |
| 2017-05-07 01:34:00 | cortisol reduces glucose-6-phosphate (G6P) flux through H6PDH by increasing luminal NADPH, thereby allowing more G6P for hydrolysis via G6Pase | 26860459 |
| 2016-08-06 11:15:00 | Inhibition of glucose-6-phosphate dehydrogenase sensitizes cisplatin-resistant cells to death. | 26337086 |
| 2016-06-04 11:49:00 | The G allele of rs6688832 in H6PD might exert potential genetic protective role against the development of PCOS, especially in overweight women. PCOS patients with AG genotype of rs6688832 might confer risk to the phenotype of hyperandrogenemia of PCOS. | 26452272 |
| Type | IDs |
|---|---|
| Synonymous | CORTRD1, G6PDH, GDH |
| Gene |
UniProtKB-ID:
G6PE_HUMAN
UniprotKB:
O95479
UniParc:
UPI0000D61E40,
UPI000013C9AD
EMBL:
BC081559,
Z98044,
CR749282,
AJ012590
Ensembl:
ENSG00000049239
KO:
hsa:9563
|
| Nucleutide sequences |
EMBL-CDS:
AAH81559.1,
CAH18137.1,
CAA10071.1
Ensembl_TRS:
ENST00000602477,
ENST00000377403
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000473348,
ENSP00000366620
RefSeq:
NP_004276.2,
XP_006711115.1,
XP_016858355.1,
XP_016858354.1,
NP_001269516.1,
XP_005263597.1
|
| Others |
UniRef100:
UniRef100_O95479
UniRef90:
UniRef90_O95479
UniRef50:
UniRef50_O95479
UniGene:
Hs.463511
CCDS:
CCDS101.1,
CCDS72697.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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