| Type | Description |
|---|---|
| Definition | ectonucleoside triphosphate diphosphohydrolase 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-02-10 10:50:00 | NTPDase2 and -3 are ecto-enzymes expressed in the enteric nervous system. Both enzymes confer protection against gut inflammation in experimental colitis and exhibit alterations in Crohn's disease. These observations suggest that purinergic signalling modulated by E-NTPDases governs neuro-immune interactions that are relevant in Crohn's disease. | 28472257 |
| 2016-08-13 10:12:00 | Despite the increased level of NTPDase1 and NTPDase3 mRNA expression in chondrogenically induced MSCs, their activity toward ATP remains quite low. | 26018728 |
| 2014-01-25 11:10:00 | NTPDase3 is the major ectonucleotidase in pancreatic beta-cells in multiple species and modulates insulin secretion by controlling activation of purinergic receptors. | 24085034 |
| 2010-06-28 12:16:00 | Cystic fibrosis epithelia exhibit >50% lower NTPDase1 activity, protein, and mRNA levels than normal epithelia, whereas these parameters are threefold higher for NTPDase3. | 20190036 |
| 2010-01-21 00:00:00 | efficiently inhibit the NTPDase3expressed in insulin secreting human pancreatic islet cells in situ | 19120451 |
| Type | IDs |
|---|---|
| Synonymous | CD39L3, HB6, NTPDase-3 |
| Gene |
UniProtKB-ID:
ENTP3_HUMAN
UniprotKB:
O75355
UniParc:
UPI0000141558,
UPI000013E75E
EMBL:
AF034840,
BC029869,
CH471055,
AC104186,
AK313322,
AF039917
Ensembl:
ENSG00000168032
KO:
hsa:956
|
| Nucleutide sequences |
EMBL-CDS:
EAW64601.1,
BAG36127.1,
AAC09236.2,
EAW64600.1,
AAC39884.1,
AAH29869.1
Ensembl_TRS:
ENST00000456402,
ENST00000301825,
ENST00000445129
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000404671,
ENSP00000301825,
ENSP00000401565
RefSeq:
NP_001278889.1,
XP_011532568.1,
NP_001239.2,
NP_001278890.1
|
| Others |
UniRef100:
UniRef100_O75355
UniRef90:
UniRef90_O75355
UniRef50:
UniRef50_O75355
UniGene:
Hs.441145
CCDS:
CCDS74919.1,
CCDS2691.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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