| Type | Description |
|---|---|
| Definition | VPS26, retromer complex component A |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:56:00 | Novel crosstalk between Vps26a and Nox4 signaling during neurogenesis. | 30464227 |
| 2018-01-27 11:14:00 | We investigated the modification of air pollution and diabetes association by a genetic risk score covering 63 T2D genes. Five single variants near GRB14, UBE2E2, PTPRD, VPS26A and KCNQ1 showed nominally significant interactions with PM10 (P<0.05). Our results suggest that genetic risk for T2D may modify susceptibility to air pollution through alterations in insulin sensitivity. | 27281273 |
| 2017-11-04 10:50:00 | The retromer complex is a highly conserved membrane trafficking assembly composed of three proteins - Vps26, Vps29 and Vps35, which are impaired in neurodegenerative diseases. (Review) | 26965691 |
| 2017-05-13 13:44:00 | X-ray crystallographic analysis of a 4-component complex comprising the VPS26 & VPS35 subunits of retromer, sorting nexin SNX3, & recycling signal from the divalent cation transporter DMT1-II; analysis identifies a binding site for canonical recycling signals at the interface between VPS26 & SNX3; shows cooperative interactions among the VPS subunits, SNX3 & cargo that couple signal-recognition to membrane recruitment. | 27889239 |
| 2016-04-30 11:56:00 | Mutagenesis studies coupled with coimmunoprecipitations revealed that retromer-mediated trafficking requires the Env cytoplasmic tail that we show binds directly to retromer components Vps35 and Vps26. | 25393110 |
| Type | IDs |
|---|---|
| Synonymous | HB58, Hbeta58, PEP8A, VPS26 |
| Gene |
UniProtKB-ID:
VP26A_HUMAN,
B4DLT1_HUMAN
UniprotKB:
O75436,
B4DLT1
UniParc:
UPI0000138BC6,
UPI00017A7380,
UPI00005D6930
EMBL:
BC022505,
CH471083,
AK315496,
BQ048905,
AL596223,
AF054179,
AK297142,
AL442635,
AK022992,
AF175266
Ensembl:
ENSG00000122958
KO:
hsa:9559
|
| Nucleutide sequences |
EMBL-CDS:
AAH22505.1,
EAW54313.1,
AAF89954.1,
BAB14351.1,
BAG37880.1,
AAC39912.1,
BAG59643.1
Ensembl_TRS:
ENST00000263559,
ENST00000373382,
ENST00000395098
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362480,
ENSP00000378532,
ENSP00000263559
RefSeq:
NP_001305875.1,
NP_004887.2,
NP_001030337.1,
NP_001305874.1,
NP_001305873.1
|
| Others |
UniRef100:
UniRef100_O75436,
UniRef100_B4DLT1
UniRef90:
UniRef90_F1SUG3,
UniRef90_O75436
UniRef50:
UniRef50_O75436,
UniRef50_Q5BKM4
UniGene:
Hs.499925
CCDS:
CCDS41536.1,
CCDS7286.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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