| Type | Description |
|---|---|
| Definition | H2A histone family member Y |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:44:00 | Upregulated mH2A1 serves as an unfavorable prognostic indicator and promotes the progress of hepatocellular carcinoma (HCC). | 33058912 |
| 2020-08-15 19:04:00 | Histone H2A variants alpha1-extension helix directs RNF168-mediated ubiquitination. | 32424115 |
| 2020-06-20 11:11:00 | Results found that macroH2A1 isoforms' mRNA levels are significantly decreased in yyelodysplastic syndromes (MDS) patients with a 5q deletion compared to other MDS groups and healthy individuals. | 31439048 |
| 2020-05-23 10:30:00 | Our data indicate that housekeeping promoters may titrate promiscuous enhancer activity to ensure normal morphogenesis. The deletion of the H2AFY promoter as a cause of Liebenberg syndrome highlights this new mutational mechanism and its role in congenital disease. | 30711920 |
| 2020-04-11 10:55:00 | These results demonstrate that, conversely, macrodomain-containing proteins, and specifically those containing macroH2A1, can regulate function through a novel mechanism that promotes both survival and efficient repair during DNA damage response. | 31636161 |
| Type | IDs |
|---|---|
| Synonymous | H2A.y, H2A/y, H2AF12M, MACROH2A1.1, mH2A1, macroH2A1.2 |
| Gene |
UniProtKB-ID:
H2AY_HUMAN
UniprotKB:
O75367
UniParc:
UPI000013E965,
UPI00000723ED,
UPI000013C951
EMBL:
AF054174,
AY134746,
AC026691,
AF044286,
BC013331,
AF041483,
BC095406,
AK023409
Ensembl:
ENSG00000113648
KO:
hsa:9555
|
| Nucleutide sequences |
EMBL-CDS:
AAC33433.1,
AAC33434.1,
BAB14565.1,
AAN08620.1,
AAC39908.1,
AAH13331.1,
AAH95406.1
Ensembl_TRS:
ENST00000312469,
ENST00000304332,
ENST00000510038,
ENST00000511689
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000423563,
ENSP00000424971,
ENSP00000310169,
ENSP00000302572
RefSeq:
XP_005272189.1,
XP_011542031.1,
XP_005272191.1,
XP_016865556.1,
XP_011542033.1,
XP_024302031.1,
XP_016865557.1,
XP_024302032.1,
NP_001035248.1,
XP_011542035.1,
NP_004884.1,
NP_613258.2,
XP_011542036.1,
XP_011542034.1,
XP_011542037.1,
XP_005272192.1,
NP_613075.1,
XP_011542032.1
|
| Others |
UniRef100:
UniRef100_O75367
UniRef90:
UniRef90_O75367
UniRef50:
UniRef50_O75367
UniGene:
Hs.420272,
Hs.599225
CCDS:
CCDS4183.1,
CCDS4184.1,
CCDS4185.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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