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9546 APBA3

9546

APBA3

amyloid beta precursor protein binding family A member 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition amyloid beta precursor protein binding family A member 3

研究结论

Date Results Publications
2021-01-16 15:55:00 Mint3 depletion restricts tumor malignancy of pancreatic cancer cells by decreasing SKP2 expression via HIF-1. 32826949
2017-01-28 10:43:00 Results suggest that NECAB3, a novel Mint3-binding protein, activates HIF-1 to promote normoxic glycolysis and tumorigenicity by forming a ternary complex with Mint3 and FIH-1. 26948053
2015-02-14 11:22:00 FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells. 24867948
2014-10-11 10:10:00 Mints are necessary for activity-induced APP and PS1 trafficking and provide insight into the cellular fate of APP in endocytic pathways essential for Abeta production. 24742670
2013-12-07 10:08:00 Strict specificity for recruitment of the Mint3 adaptor by APP at the Golgi, a critical role for Tyr-682 (within the YENPTY motif) in Mint3 recruitment and export of APP from the Golgi, are demonstrated. 23965993

名称对应

Type IDs
Synonymous MGC:15815, X11L2, mint3
Gene
UniProtKB-ID: APBA3_HUMAN
UniprotKB: O96018
UniParc: UPI0000125C0D
EMBL: AB021638, AB023431, BC086306, AF029110, AC005954
Ensembl: ENSG00000011132
KO: hsa:9546
Nucleutide sequences
EMBL-CDS: BAA83094.1, BAA74430.1, AAC17979.1, AAH86306.1, AAC72275.1
Ensembl_TRS: ENST00000316757
Protein sequencees
Ensembl_PRO: ENSP00000315136
RefSeq: XP_006723013.1, NP_004877.1, XP_006723014.1
Others
UniRef100: UniRef100_O96018
UniRef90: UniRef90_O96018
UniRef50: UniRef50_O96018
UniGene: Hs.25527, Hs.465607
CCDS: CCDS12110.1

全选

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研究热度

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