| Type | Description |
|---|---|
| Definition | tumor protein p53 inducible protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-16 11:00:00 | expression of PIG3 is frequently reduced in gastric cancer (GC) tissue, and PIG3 suppressed human GC growth through p53- mediated apoptosis; PIG3 may act as a potential diagnostic marker and a potential therapeutic target of GC | 30334411 |
| 2019-01-05 10:47:00 | Study found that PIG3 expression was positively associated with lymph node metastasis from lung adenocarcinoma (LUAD) but not from lung squamous cell carcinoma (LUSC). Further data revealed a role for PIG3 in inducing LUAD metastasis, and its role as a new FAK regulator, suggesting that it could be considered as a novel prognostic biomarker. | 30281878 |
| 2017-12-16 12:31:00 | Results revealed that PIG3 expression levels positively correlated with poor prognosis of non-small cell lung cancer (NSCLC) patients and indicate that PIG3 promotes NSCLC progression. | 28259183 |
| 2017-12-16 11:10:00 | Data suggest that PIG3 was involved in HIF-1alpha regulation, and indicate a signaling pathway of PIG3/HIF-1alpha in the regulation of cell migration in renal cell carcinoma. | 27029070 |
| 2017-04-08 10:48:00 | our data suggest that high expression of p53-inducible gene 3 is significant for glioblastoma inhibition and p53-inducible gene 3 independently indicates good prognosis in patients, which might be a novel prognostic biomarker or potential therapeutic target in glioblastoma. | 28351326 |
| Type | IDs |
|---|---|
| Synonymous | PIG3 |
| Gene |
UniProtKB-ID:
QORX_HUMAN,
B4DMQ7_HUMAN
UniprotKB:
Q53FA7,
B4DMQ7
UniParc:
UPI000006D860,
UPI0000377FFB,
UPI0000EE2288
EMBL:
AF010317,
AC008073,
DQ232851,
BT007149,
AK297579,
CH471053,
AK223382,
BC000474,
AF010309,
AY371700
Ensembl:
ENSG00000115129
KO:
hsa:9540
|
| Nucleutide sequences |
EMBL-CDS:
ABB02183.1,
AAP35813.1,
AAC39535.1,
AAY14665.1,
EAX00763.1,
EAX00766.1,
AAQ90166.1,
EAX00762.1,
AAH00474.1,
BAD97102.1,
AAC39528.1,
EAX00765.1,
BAG59969.1
Gene_ORFName:
hCG_22385
Ensembl_TRS:
ENST00000335934,
ENST00000238721,
ENST00000407482
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000337834,
ENSP00000384414,
ENSP00000238721
RefSeq:
XP_006712213.1,
NP_671713.1,
NP_001193731.1,
NP_004872.2,
XP_024309017.1,
XP_005264707.1
|
| Others |
UniRef100:
UniRef100_B4DMQ7,
UniRef100_Q53FA7
UniRef90:
UniRef90_Q53FA7,
UniRef90_B4DMQ7
UniRef50:
UniRef50_Q53FA7,
UniRef50_A0A673VBJ4
UniGene:
Hs.50649,
Hs.733381
CCDS:
CCDS1708.1,
CCDS56112.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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