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954 ENTPD2

954

ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition ectonucleoside triphosphate diphosphohydrolase 2

研究结论

Date Results Publications
2018-05-19 11:12:00 In oviducts, remarkably, ectonucleoside triphosphate diphosphohydrolase 2 (NTPDase2), with the ability to hydrolyze ATP to AMP, are expressed in ciliated epithelial cells but with different subcellular localization. 29273916
2018-02-24 10:23:00 Hypoxia upregulates ENTPD2 through HIF-1alpha in hepatocellular carcinoma and subsequently leading to the accumulation of extracellular 5'-AMP, which maintains myeloid-derived suppressor cells undifferentiated. 28894087
2018-02-10 10:50:00 NTPDase2 and -3 are ecto-enzymes expressed in the enteric nervous system. Both enzymes confer protection against gut inflammation in experimental colitis and exhibit alterations in Crohn's disease. These observations suggest that purinergic signalling modulated by E-NTPDases governs neuro-immune interactions that are relevant in Crohn's disease. 28472257
2010-01-21 00:00:00 NTPDase2 preferentially hydrolyzes nucleoside triphosphates. 15496502
2010-01-21 00:00:00 down-regulation in biliary cirrhosis 15651265

名称对应

Type IDs
Synonymous CD39L1, NTPDase-2
Gene
UniProtKB-ID: ENTP2_HUMAN
UniprotKB: Q9Y5L3
UniParc: UPI000002A8E5, UPI0003D19F66, UPI0000001C45
EMBL: CH471090, AF144748, BC035738, AL807752, U91510, EF495152
Ensembl: ENSG00000054179
KO: hsa:954
Nucleutide sequences
EMBL-CDS: EAW88337.1, ABP58644.1, AAB81013.1, AAH35738.1, AAD40239.1, EAW88336.1
Ensembl_TRS: ENST00000355097, ENST00000312665
Protein sequencees
Ensembl_PRO: ENSP00000312494, ENSP00000347213
RefSeq: NP_982293.1, XP_011517514.1, NP_001237.1
Others
UniRef100: UniRef100_Q9Y5L3
UniRef90: UniRef90_Q9Y5L3
UniRef50: UniRef50_Q9Y5L3
UniGene: Hs.123036
CCDS: CCDS7026.1, CCDS7025.1

全选

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