| Type | Description |
|---|---|
| Definition | prostaglandin E synthase |
| Date | Results | Publications |
|---|---|---|
| 2020-02-08 10:40:00 | Studied the role that microsomal prostaglandin E synthase-1 (mPGES-1) derived prostaglandin E2 (PGE2) plays in cell migration in the pathogenesis of Hirschsprung disease. Results showed mPGES-1 derived PGE2 decreased the relative expression of EP2 and and caused damage to cytoskeleton. | 30814036 |
| 2020-01-18 11:01:00 | We found that PTGES is overexpressed in the first stages of AGA. | 30730082 |
| 2019-12-28 11:34:00 | mPGES-1 is induced in dopaminergic neurons of postmortem Parkinson's disease (PD) patients and PD model mice. Microsomal prostaglandin E synthase-1 is a critical factor in dopaminergic neurodegeneration in Parkinson's disease. | 30423474 |
| 2019-09-28 13:11:00 | Atherosclerotic plaque constituents 27-hydroxycholesterol and 4-hydroxynonenal cause up-regulation of COX-2 and mPGES-1. | 30312760 |
| 2019-04-23 08:49:00 | The DHEA metabolite 7beta-hydroxy-epiandrosterone exerts anti-estrogenic effects on breast cancer cell lines. | 22342541 |
| Type | IDs |
|---|---|
| Synonymous | MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1 |
| Gene |
UniProtKB-ID:
PTGES_HUMAN
UniprotKB:
O14684
UniParc:
UPI00001328DD
EMBL:
AL592219,
BC008280,
AF027740,
AJ271802,
AL590369,
AJ271804,
AF010316,
AJ271803,
AK311947,
EF543149
Ensembl:
ENSG00000148344
KO:
hsa:9536
|
| Nucleutide sequences |
EMBL-CDS:
AAB82299.1,
AAC39534.1,
CAB72099.1,
AAH08280.1,
BAG34888.1,
ABQ01233.1
Ensembl_TRS:
ENST00000340607
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000342385
RefSeq:
NP_004869.1
|
| Others |
UniRef100:
UniRef100_O14684
UniRef90:
UniRef90_O14684
UniRef50:
UniRef50_O14684
UniGene:
Hs.146688
CCDS:
CCDS6927.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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