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9528 TMEM59

9528

TMEM59

transmembrane protein 59

protein-coding

Homo sapiens

基因描述

Type Description
Definition transmembrane protein 59

研究结论

Date Results Publications
2021-02-27 13:53:00 Dcf1 alleviates C99-mediated deficits in drosophila by reducing the cleavage of C99. 32540098
2020-12-19 13:44:00 The Chlamydia effector CT622/TaiP targets a nonautophagy related function of ATG16L1. 33055216
2019-01-26 11:47:00 Results provide evidence that DCF1 plays an important role in controlling neuroblastoma (NB) tumor viability, promoting cell apoptosis, and inhibiting tumorigenesis in vivo. DCF1 could be a potential new inhibitor for components of the ERK1/2 signaling pathway and helped understand the molecular mechanism of NB. 30365123
2018-08-18 11:01:00 identify the single-span membrane protein TMEM59 as an interactor of FZD and LRP6 and a positive regulator of Wnt signaling. Mechanistically, TMEM59 promotes the formation of multimeric Wnt-FZD assemblies via intramembrane interactions. 29632210
2018-07-28 11:15:00 DCF1 subcellular localization and its function in mitochondria 29074393

名称对应

Type IDs
Synonymous C1orf8, DCF1, HSPC001, PRO195, UNQ169
Gene
UniProtKB-ID: TMM59_HUMAN, Q5T6Z8_HUMAN, Q5T703_HUMAN, D3DQ48_HUMAN
UniprotKB: Q9BXS4, Q5T6Z8, Q5T703, D3DQ48
UniParc: UPI00002043BF, UPI0000001BF9, UPI000034F5E2, UPI000006F218
EMBL: BC003106, AL353898, AF290615, KF495954, BC095464, CH471059, AK075187, AF047439, BC016374, AK075505, AY359029
Ensembl: ENSG00000116209
KO: hsa:9528
Nucleutide sequences
EMBL-CDS: AAH95464.1, BAC11658.1, BAG52079.1, AAQ89388.1, AAH03106.1, AAC39890.1, AAK28026.1, AAH16374.1, EAX06707.1, EAX06704.1, EAX06706.1, EAX06710.1, EAX06709.1
Gene_ORFName: HSPC001, UNQ169/PRO195, hCG_33694, hCG_33694
Ensembl_TRS: ENST00000234831, ENST00000371344, ENST00000371341, ENST00000371348, ENST00000371337
Protein sequencees
Ensembl_PRO: ENSP00000234831, ENSP00000360395, ENSP00000360399, ENSP00000360392, ENSP00000360388
RefSeq: NP_001291979.1, NP_001291981.1, NP_001291972.1, NP_001291980.1, NP_001291995.1, NP_004863.2, NP_001291978.1
Others
UniRef100: UniRef100_D3DQ48, UniRef100_Q9BXS4, UniRef100_Q5T703, UniRef100_Q5T6Z8
UniRef90: UniRef90_Q9BXS4, UniRef90_Q5T703, UniRef90_Q3T0Q2
UniRef50: UniRef50_Q3T0Q2, UniRef50_Q9BXS4, UniRef50_Q5T703
UniGene: Hs.523262
CCDS: CCDS586.1

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