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951476 HCVgp2

951476

HCVgp2

protein F

protein-coding

Hepatitis C virus genotype 1

基因描述

Type Description
Definition protein F

研究结论

Date Results Publications
2017-08-05 11:49:00 the prevalence of anti-core+1 antibodies was significantly increased in Hepatitis C patients with advanced cirrhosis, as well as in cirrhotic patients with Hepatitis C virus-associated hepatocellular carcinoma, supporting the possible association of core +1/ARF protein with the progression of Hepatitis C virus-induced cirrhosis and carcinogenesis. 28708052
2017-08-05 10:17:00 a novel mechanism of pattern recognition receptor modulation by HCV and suggests a biological function of the HCV alternate reading frame in the modulation of host innate immunity 27404108
2016-03-26 11:53:00 Thus, a possible new strategy of T cell modulation is recognized wherein effector T cells are caused to be dysfunctional by hepatitis C virus-derived antigens F or core. 26133045
2015-12-19 11:41:00 These results suggest the potential involvement of F and core antigens in increasing the frequency of CD4+CD25+FoxP3+ T cell-like population and IL-10-producing CD4+CD25+ T cells which may be associated with hepatitis C virus persistent infection. 25862675
2015-06-20 12:44:00 Authors demonstrate for the first time expression of core+1/ARF protein in the context of a bicistronic JFH1-based replicon and report the production of two isoforms, core+1/L (long) and core+1/S (short), with different kinetics. 25694591

名称对应

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