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950 SCARB2

950

SCARB2

scavenger receptor class B member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition scavenger receptor class B member 2

研究结论

Date Results Publications
2019-12-28 11:36:00 Our findings show disease-specific deregulation of TFEB and SCARB2 expression affecting alternative promoter usage and alternative splicing in Lewy body diseases 31116970
2019-12-14 10:09:00 Study provides multiple lines of evidence that LIMP-2 participates in lipid transport from lysosomes by transporting cholesterol (and possibly also other lipid species) through its luminal cavity to the lysosomal membrane and later to lipid droplets. Data indicate that LIMP-2 operates in parallel with Niemann Pick (NPC)-proteins, mediating a slower mode of lysosomal cholesterol export. 31387993
2019-09-07 11:33:00 Results provide evidence that SCARB2 is essential for the virulence of Enterovirus &1. 29848584
2019-06-08 11:05:00 Here, we report the EV71-SCARB2 complex structure determined at 3.4 A resolution using cryo-electron microscopy. This reveals that SCARB2 binds EV71 on the southern rim of the canyon, rather than across the canyon, as predicted. 30531980
2019-04-27 10:21:00 SCARB2 polymorphisms (rs6824953 and rs11097262) were associated with susceptibility to EV71 infection (OR 1.60, 95% CI 1.07-2.39; and OR 1.64, 95% CI 1.09-2.47, respectively). 30395634

名称对应

Type IDs
Synonymous AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII
Gene
UniProtKB-ID: SCRB2_HUMAN, A0A024RDG6_HUMAN
UniprotKB: Q14108, A0A024RDG6
UniParc: UPI0001AE7436, UPI0000032D38
EMBL: AK296519, CH471057, BT006939, AK313016, AC034139, BC021892, AC110795, D12676
Ensembl: ENSG00000138760
KO: hsa:950
Nucleutide sequences
EMBL-CDS: AAH21892.1, BAG59150.1, EAX05779.1, AAP35585.1, BAG35851.1, BAA02177.1, EAX05781.1, EAX05780.1
Gene_ORFName: hCG_23840
Ensembl_TRS: ENST00000264896, ENST00000452464
Protein sequencees
Ensembl_PRO: ENSP00000399154, ENSP00000264896
RefSeq: NP_005497.1, NP_001191184.1
Others
UniRef100: UniRef100_Q14108
UniRef90: UniRef90_Q14108
UniRef50: UniRef50_Q14108
UniGene: Hs.349656
CCDS: CCDS56335.1, CCDS3577.1

全选

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