| Type | Description |
|---|---|
| Definition | 5-methylcytosine-specific restriction enzyme subunit McrB |
| Date | Results | Publications |
|---|---|---|
| 2019-10-26 11:10:00 | Study present the structure of the AAA+ domain of Escherichia coli McrB in complex with McrC at 3.6 A resolution using cryo-electron microscopy, which reveals the coupling between the endonuclease and the motor and the mechanism of activation of the GTPase. | 31296862 |
| 2019-08-24 10:39:00 | Nucleotide-dependent oligomerisation of McrB precedes GTP hydrolysis. | 30521042 |
| 2019-06-29 12:07:00 | Cocrystal structures of endonuclease McrB (McrB)-N bound to DNA oligoduplexes containing 5-methylcytosine (5mC), 5-hydroxymethylcytosine (5hmC) and N4-methylcytosine (4mC) with relative affinity. | 30194838 |
| 2012-11-17 10:24:00 | In the McrB-N structure in complex with methylated DNA, the 5mC base is flipped out from the DNA duplex and positioned within a binding pocket. | 22570415 |
| 2012-10-13 10:10:00 | Deletion of penicillin-binding protein 1b impairs biofilm formation and motility. | 22349271 |
| Type | IDs |
|---|---|
| Synonymous | ECK4336, rglB |
| Gene |
UniProtKB-ID:
MCRB_ECOLI
UniprotKB:
P15005
UniParc:
UPI0000D7A4D2,
UPI000012EDBD
EMBL:
U00096,
U14003,
M24927,
AP009048,
M58752
EnsemblGenome:
BAE78336,
b4346
KO:
eco:b4346,
ecj:JW5871
|
| Nucleutide sequences |
EMBL-CDS:
AAA97243.1,
AAA24145.1,
BAE78336.1,
AAA24142.1,
AAC77302.2
EnsemblGenome_TRS:
BAE78336,
AAC77302
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE78336,
AAC77302
RefSeq:
NP_418766.4
|
| Others |
UniRef100:
UniRef100_P15005
UniRef90:
UniRef90_P15005
UniRef50:
UniRef50_P15005
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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