| Type | Description |
|---|---|
| Definition | thymidylate synthase |
| Date | Results | Publications |
|---|---|---|
| 2016-09-24 11:32:00 | The measured activities of the E. coli thymidylate synthase (TS) mutants imply that conservation of electrostatics in the region of the active site is important for the activity of TS. | 26612036 |
| 2014-03-15 10:12:00 | Data indicate the BGC 945 formed complexes and inhibited E coli and human thymidylate synthase (TS). | 23710599 |
| 2010-01-21 00:00:00 | findings suggested that Y94 is part of a H-bond network that plays a critical role at a step between the proton and the hydride transfers, presumably the dissociation of H4folate from the covalently bound intermediate. | 17999469 |
| 2007-11-05 21:39:00 | N-terminus verified by Edman degradation on complete protein | 6308660 |
| Type | IDs |
|---|---|
| Synonymous | ECK2823 |
| Gene |
UniProtKB-ID:
TYSY_ECOLI
UniprotKB:
P0A884
UniParc:
UPI000003EB17
EMBL:
U29581,
X03966,
AP009048,
J01710,
U00096
EnsemblGenome:
b2827,
BAE76896
KO:
eco:b2827,
ecj:JW2795
|
| Nucleutide sequences |
EMBL-CDS:
AAC75866.1,
AAA24675.1,
CAA27600.1,
BAE76896.1,
AAB40474.1
EnsemblGenome_TRS:
BAE76896,
AAC75866
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC75866,
BAE76896
RefSeq:
NP_417304.1
|
| Others |
UniRef100:
UniRef100_A7ZQT3
UniRef90:
UniRef90_A8AP42
UniRef50:
UniRef50_A8AP42
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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