leuO - DNA-binding transcriptional dual regulator LeuO-BMKCloudï½ç¾è¿å®¢äº

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949034 leuO

基因描述

Type	Description
Definition	DNA-binding transcriptional dual regulator LeuO

研究结论

Date	Results	Publications
2019-12-14 12:35:00	DNA-binding transcriptional dual regulator LeuO (LeuO) is a tetramer that is formed by dimerization of the N-terminal DNA-binding domain (DBD) and C-terminal effector-binding domain (EBD).	31184713
2017-09-23 11:02:00	BglJ-RcsB activates leuO, while LeuO inhibits activation by BglJ-RcsB. Furthermore, LeuO activates expression of bglJ, which is likewise H-NS repressed.	27695690
2012-08-11 10:32:00	RcsB-BglJ binds to the leuO promoter region and activates one of two leuO promoters.	22295907
2012-01-28 10:57:00	LeuO is a major player in antagonistic interplay against the universal silencer H-NS.	21883529
2010-12-11 11:11:00	H-NS and LeuO are antagonistic regulators of CRISPR-based immunity.	20659289

名称对应

Type	IDs
Synonymous	ECK0078
Gene	UniProtKB-ID: LEUO_ECOLI UniprotKB: P10151 UniParc: UPI000012E5AC EMBL: M12891, M21150, X55034, AP009048, U00096 EnsemblGenome: b0076, BAB96645 KO: eco:b0076, ecj:JW0075
Nucleutide sequences	EMBL-CDS: AAA85299.1, CAA38853.1, BAB96645.2, AAC73187.2, AAA83880.1 EnsemblGenome_TRS: BAB96645, AAC73187
Protein sequencees	EnsemblGenome_PRO: BAB96645, AAC73187 RefSeq: NP_414618.4
Others	UniRef100: UniRef100_P10151 UniRef90: UniRef90_P10151 UniRef50: UniRef50_P10151

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mRNA

Protein

UniprotKB

Description

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Pubmed编号	文献信息	发表日期	相关基因
31184713	Characterization of the pleiotropic LysR-type transcription regulator LeuO of Escherichia coli. Nucleic Acids Res. Susann M Fragel , Anna Montada , Ralf Heermann , Ulrich Baumann , Magdalena Schacherl , Karin Schnetz	2019-08-22	-
27695690	Correlation of Antagonistic Regulation of leuO Transcription with the Cellular Levels of BglJ-RcsB and LeuO in Escherichia coli. Front Cell Infect Microbiol Hannes Breddermann , Karin Schnetz	2016-01-01	-
24561554	The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. Seesandra V Rajagopala , Patricia Sikorski , Ashwani Kumar , Roberto Mosca , James Vlasblom , Roland Arnold , Jonathan Franca-Koh , Suman B Pakala , Sadhna Phanse , Arnaud Ceol , Roman HÃ¤user , Gabriella Siszler , Stefan Wuchty , Andrew Emili , Mohan Babu , Patrick Aloy , Rembert Pieper , Peter Uetz	2014-03-01	-
22295907	RcsB-BglJ activates the Escherichia coli leuO gene, encoding an H-NS antagonist and pleiotropic regulator of virulence determinants. Mol. Microbiol. Thomas Stratmann , Ãmit Pul , Reinhild Wurm , Rolf Wagner , Karin Schnetz	2012-03-01	hns, rcsB, bglJ, leuO
21883529	Novel roles of LeuO in transcription regulation of E.âcoli genome: antagonistic interplay with the universal silencer H-NS. Mol. Microbiol. Tomohiro Shimada , Arnaud Bridier , Romain Briandet , Akira Ishihama	2011-10-01	hns, leuO
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
20659289	H-NS-mediated repression of CRISPR-based immunity in Escherichia coli K12 can be relieved by the transcription activator LeuO. Mol. Microbiol. Edze R Westra , Umit Pul , Nadja Heidrich , Matthijs M Jore , Magnus Lundgren , Thomas Stratmann , Reinhild Wurm , Amanda Raine , Melina Mescher , Luc Van Heereveld , Marieke Mastop , E Gerhart H Wagner , Karin Schnetz , John Van Der Oost , Rolf Wagner , Stan J J Brouns	2010-09-01	hns, leuO
19429622	Involvement of the leucine response transcription factor LeuO in regulation of the genes for sulfa drug efflux. J Bacteriol Tomohiro Shimada , Kaneyoshi Yamamoto , Akira Ishihama	2009-07-01	-
18055596	Regulation of the yjjQ-bglJ operon, encoding LuxR-type transcription factors, and the divergent yjjP gene by H-NS and LeuO. J. Bacteriol. Thomas Stratmann , S Madhusudan , Karin Schnetz	2008-02-01	hns, yjjP, bglJ, yjjQ, leuO
16738553	Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi	2006-01-01	pmrR, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeB, yohO, arnE, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, wecF, yigE, blr, yggP, cpxP, hdfR, thiS, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, yhaM, tdcG, ytfR, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yneM, ykfM, ylcI, yciY, yncL, ylcH, ynhF, yciZ, ydgU, ypfM, ymgI, ymgJ, dinQ

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