| Type | Description |
|---|---|
| Definition | peptide chain release factor RF1 |
| Date | Results | Publications |
|---|---|---|
| 2019-07-13 10:45:00 | Study used time-resolved cryo-EM to visualize transient compact forms of RF1 and RF2 at 3.5 and 4 A resolution, respectively, in the codon-recognizing ribosome complex on the native pathway. About 25% of complexes have RFs in the compact state at 24 ms reaction time, and within 60 ms virtually all ribosome-bound RFs are transformed to their extended forms. | 31189921 |
| 2019-04-20 11:30:00 | Ribosome termination complexes that carry two factors, RF1-RF3 or RF2-RF3, are dynamic and fluctuate between non-rotated and rotated states, whereas each factor alone has its distinct signature on ribosome dynamics and conformation. | 29889659 |
| 2018-05-12 10:57:00 | both RF1 binding and RF2 binding are sufficient to shift the population of posthydrolysis ribosome complexes from primarily the rotated to the nonrotated state only when a cognate stop codon is present in the A-site. | 29499110 |
| 2017-05-27 10:52:00 | Data show that peptide chain release factor RF-3 (RF3) hydrolyzes GTP and dissociates from the ribosome before peptide chain release factor RF-1 (RF1)dissociation. | 27779391 |
| 2016-08-20 12:06:00 | These results indicate that RF1 undergoes a large conformational change from a closed to an open form upon binding to the ribosome. | 26827724 |
| Type | IDs |
|---|---|
| Synonymous | ECK1199, sueB, uar, ups? |
| Gene |
UniProtKB-ID:
RF1_ECOLI
UniprotKB:
P0A7I0
UniParc:
UPI0000133730
EMBL:
M30785,
M11519,
M25323,
U00096,
D28567,
AP009048,
U18555
EnsemblGenome:
b1211,
BAA36069
KO:
eco:b1211,
ecj:JW1202
|
| Nucleutide sequences |
EMBL-CDS:
BAA05914.1,
AAA23955.1,
AAC43437.1,
BAA36069.1,
AAA24519.1,
AAC74295.1
EnsemblGenome_TRS:
BAA36069,
AAC74295
|
| Protein sequencees |
EnsemblGenome_PRO:
BAA36069,
AAC74295
RefSeq:
NP_415729.1
|
| Others |
UniRef100:
UniRef100_A7ZKY5
UniRef90:
UniRef90_A7ZKY5
UniRef50:
UniRef50_Q2KZZ3
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
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