| Type | Description |
|---|---|
| Definition | DNA replication protein DnaC |
| Date | Results | Publications |
|---|---|---|
| 2019-07-20 12:52:00 | Data show how DnaC opens the DnaB ring and represses the helicase prior to DNA binding and how DnaC ATPase activity is reciprocally regulated by DnaB and DNA. | 30797687 |
| 2018-12-22 10:05:00 | we propose that DnaC controls the ability of DnaB to interact with primase by modifying the conformation of the N-terminal domain of DnaB | 29070678 |
| 2016-08-20 10:07:00 | Thus, imbalances in levels of the replicative helicase and helicase loader can inhibit replication both via inhibition of DnaB6-DnaC6 complex formation with excess DnaB, as shown here, and promotion of formation of DnaB6-DnaC6 complexes with excess DnaC. | 26812209 |
| 2013-06-22 12:10:00 | Data demonstrate that DnaC opens DnaB by a mechanism akin to that of polymerase clamp loaders and indicate that bacterial replicative helicases, like their eukaryotic counterparts, possess autoregulatory elements that influence how hexameric motor domains are loaded onto and unwind DNA. | 23562643 |
| 2010-01-21 00:00:00 | These results suggest that in the presence of ATP in vivo, the DnaB6 x DnaC6 complex should be more efficient in binding DNA as well as in loading DnaB onto the ssDNA than DnaB helicase itself. | 16981710 |
| Type | IDs |
|---|---|
| Synonymous | ECK4351, dnaD |
| Gene |
UniProtKB-ID:
DNAC_ECOLI
UniprotKB:
P0AEF0
UniParc:
UPI0000129564
EMBL:
U00096,
AP009048,
U14003,
J04030
EnsemblGenome:
b4361,
BAE78351
KO:
eco:b4361,
ecj:JW4325
|
| Nucleutide sequences |
EMBL-CDS:
AAA23700.1,
AAC77317.1,
AAA97260.1,
BAE78351.1
EnsemblGenome_TRS:
BAE78351,
AAC77317
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE78351,
AAC77317
RefSeq:
NP_418781.1
|
| Others |
UniRef100:
UniRef100_P0AEF2
UniRef90:
UniRef90_P0AEF2
UniRef50:
UniRef50_P0AEF2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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