| Type | Description |
|---|---|
| Definition | anti-adaptor protein IraD, inhibitor of sigma(S) proteolysis |
| Date | Results | Publications |
|---|---|---|
| 2019-09-07 12:22:00 | crystal structure of RssB bound to an antiadaptor, the DNA damage-inducible IraD; demonstrate that (1) in the presence of IraD, RssB adopts predominantly a closed conformation; (2) IraD contacts both domains of RssB; (3) the interactions observed in the structure are crucial for blocking sigmaS degradation in vivo and in vitro | 30975721 |
| 2018-04-28 11:51:00 | findings show that CsrA employs a novel regulatory mechanism to repress translation of iraD; CsrA binds to four sites in the iraD leader transcript but does not directly occlude ribosome binding to the iraD SD sequence; instead, CsrA represses translation of a short open reading frame encoded upstream of iraD, causing repression of iraD translation | 28851853 |
| 2010-04-12 02:13:00 | iraD transcription is induced by DNA damage by a mechanism independent of the SOS response; IraD promoteS accumulation of the alternative transcription sigma factor, RpoS | 19124769 |
| 2010-01-21 00:00:00 | These results suggest that the induction of RpoS during transition to stationary phase and by (p)ppGpp occurs at least partially through IraD. | 19820090 |
| Type | IDs |
|---|---|
| Synonymous | ECK4317, yjiD |
| Gene |
UniProtKB-ID:
IRAD_ECOLI
UniprotKB:
P39375
UniParc:
UPI000013B5AD
EMBL:
U00096,
U14003,
AP009048
EnsemblGenome:
BAE78319,
b4326
KO:
eco:b4326,
ecj:JW5782
|
| Nucleutide sequences |
EMBL-CDS:
AAA97222.1,
BAE78319.1,
AAC77282.2
EnsemblGenome_TRS:
AAC77282,
BAE78319
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE78319,
AAC77282
RefSeq:
NP_418746.4
|
| Others |
UniRef100:
UniRef100_C4ZT14
UniRef90:
UniRef90_Q8XBA4
UniRef50:
UniRef50_Q8XBA4
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30975721 |
Structural basis for inhibition of a response regulator of ÏS stability by a ClpXP antiadaptor. Genes Dev. Victoria Dorich , Christiane Brugger , Arti Tripathi , Joel R Hoskins , Song Tong , Margaret M Suhanovsky , Amita Sastry , Sue Wickner , Susan Gottesman , Alexandra M Deaconescu |
2019-06-01 | - |
| 28851853 |
mBio Hongmarn Park , Louise C McGibbon , Anastasia H Potts , Helen Yakhnin , Tony Romeo , Paul Babitzke |
2017-08-29 | - |
| 19820090 |
Growth phase and (p)ppGpp control of IraD, a regulator of RpoS stability, in Escherichia coli. J. Bacteriol. Houra Merrikh , Alexander E Ferrazzoli , Susan T Lovett |
2009-12-01 |
dksA,
rpoS,
relA,
spoT,
iraD
|
| 19124769 |
A DNA damage response in Escherichia coli involving the alternative sigma factor, RpoS. Proc Natl Acad Sci U S A Houra Merrikh , Alexander E Ferrazzoli , Alexandre Bougdour , Anique Olivier-Mason , Susan T Lovett |
2009-01-13 | - |
| 18383615 |
Mol. Microbiol. Alexandre Bougdour , Christofer Cunning , Patrick Jean Baptiste , Thomas Elliott , Susan Gottesman |
2008-04-01 | - |
| 17509919 |
Multi-dimensional gene target search for improving lycopene biosynthesis in Escherichia coli. Metab Eng Yong-Su Jin , Gregory Stephanopoulos |
2007-07-01 | - |
| 17222132 |
Temporal gene-expression in Escherichia coli K-12 biofilms. Environ. Microbiol. Joanna Domka , Jintae Lee , Tarun Bansal , Thomas K Wood |
2007-02-01 |
gatR,
cpxP,
yedN,
cysW,
ygaQ,
yfjI,
yaaW,
aceK,
ais,
ompX,
prpR,
tauD,
tauA,
ymgC,
tfaD,
ybcV,
stfR,
citC,
citA,
sucA,
sdhC,
ariR,
sdhA,
citD,
aspC,
hyaD,
hyaA,
hyaC,
cbdA,
bluR,
narG,
prpD,
ydeM,
adhP,
ydeQ,
eamA,
fumC,
glsA,
torC,
astC,
astE,
astD,
astA,
torT,
wcaD,
gatC,
gatB,
gatZ,
yafU,
ykfI,
cysU,
cysP,
hyfG,
grcA,
ypjF,
cysN,
cysH,
cysI,
cysJ,
hyfC,
kbaY,
agaC,
agaB,
acrS,
yhcA,
acrF,
gadE,
hdeD,
hdeB,
gadA,
gadW,
dctA,
gyrB,
phoU,
aceA,
frdA,
mpl,
iraD,
ymgA,
ykfA
|
| 16397293 |
Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner |
2006-01-01 |
pmrR,
yfaS,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeF,
yoeB,
yohO,
arnE,
ypdJ,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
yifN,
wecF,
yigE,
blr,
yggP,
cpxP,
ygaY,
hdfR,
thiS,
yedN,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
glvC,
yhaM,
tdcG,
ytfR,
yehH,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
gapC,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
yedS,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yaiX,
yoeA,
yneM
|
| 16738553 |
Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi |
2006-01-01 |
pmrR,
torI,
yaeP,
ykfH,
ykgO,
ylcG,
rzoD,
ybdZ,
cydX,
gnsA,
insA,
ymgF,
ymiA,
yciX,
rzoR,
ynfO,
yniD,
yobH,
yoeB,
yohO,
arnE,
ypeB,
ypfN,
ypjJ,
arfA,
yheV,
ysaB,
sgcB,
yjhX,
ytjA,
yibT,
yicS,
yidD,
yifL,
ghoT,
yjjZ,
mntS,
iroK,
wecF,
yigE,
blr,
yggP,
cpxP,
hdfR,
thiS,
greB,
rtcA,
smf,
ygcU,
ypjK,
hokE,
sslE,
glcF,
glcE,
yhaM,
tdcG,
ytfR,
hokB,
ldrD,
hokA,
ldrA,
ldrB,
ecnA,
ecnB,
yfjD,
yhdP,
yjjV,
cysW,
hokC,
ghxQ,
tatD,
yjdP,
cutC,
nirC,
frlC,
aroK,
gntU,
dgoD,
dgoA,
dgoR,
yigL,
ldrC,
ylbE,
ydbJ,
yeiW,
yehK,
yneM,
ykfM,
ylcI,
yciY,
yncL,
ylcH,
ynhF,
yciZ,
ydgU,
ypfM,
ymgI,
ymgJ,
dinQ
|
| 15225322 |
Mol. Microbiol. Hanjing Yang , Erika Wolff , Mandy Kim , Amy Diep , Jeffrey H Miller |
2004-07-01 |
dinB,
seqA,
mprA,
iraM,
paaX,
yfjY,
mutS,
rpoS,
dam,
recG,
recQ,
uvrD,
appY,
dnaT,
iraD
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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