pmbA - metalloprotease PmbA-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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948750 pmbA

基因描述

Type	Description
Definition	metalloprotease PmbA

研究结论

Date	Results	Publications
2018-03-24 12:02:00	Study show that TldD and TldE proteins form a heterodimeric metalloprotease where the catalytic metal, which can be zinc or iron, is coordinated by residues of TldD only. The proteolytic activity is observed when both TldD and TldE are present. The unfolded polypeptides are fed through a narrow channel into the active site and processively truncated through the cleavage of short peptides from the N-terminal end.	28943336

名称对应

Type	IDs
Synonymous	ECK4230, mcb, tldE
Gene	UniProtKB-ID: PMBA_ECOLI UniprotKB: P0AFK0 UniParc: UPI0000131CAF EMBL: U00096, AP009048, D44452, U14003, X54152 EnsemblGenome: b4235, BAE78235 KO: ecj:JW4194, eco:b4235
Nucleutide sequences	EMBL-CDS: AAA97132.1, BAE78235.1, AAC77192.1, CAA38091.1, BAA07915.1 EnsemblGenome_TRS: AAC77192, BAE78235
Protein sequencees	EnsemblGenome_PRO: BAE78235, AAC77192 RefSeq: NP_418656.1
Others	UniRef100: UniRef100_P0AFK1 UniRef90: UniRef90_P0AFK1 UniRef50: UniRef50_P45077

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
28943336	The Origins of Specificity in the Microcin-Processing Protease TldD/E. Structure Dmitry Ghilarov , Marina Serebryakova , Clare E M Stevenson , Stephen J Hearnshaw , Dmitry S Volkov , Anthony Maxwell , David M Lawson , Konstantin Severinov	2017-10-03	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18304323	Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics Yasushi Ishihama , Thorsten Schmidt , Juri Rappsilber , Matthias Mann , F Ulrich Hartl , Michael J Kerner , Dmitrij Frishman	2008-01-01	-
17187058	Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation. Nat. Biotechnol. Peng Lu , Christine Vogel , Rong Wang , Xin Yao , Edward M Marcotte	2007-01-01	sspA, talB, dnaK, dnaJ, rpsT, ileS, dapB, carB, ftsZ, murE, aceF, acpP, surA, secA, can, aceE, panB, argF, lpxA, dksA, lpd, erpA, skp, dapD, acnB, tsf, glnH, fabZ, metQ, accA, galM, sodB, panC, pyrH, codA, opgG, pepD, tauB, eno, proC, phoR, thiI, gpmA, leuC, tig, clpP, clpX, lon, adk, htpG, acrB, trpD, apt, ydgH, rplT, purK, ompT, thrC, ybeD, ahpC, purR, glf, serA, miaB, pgm, seqA, rfbB, iscR, asnB, mprA, fldA, fur, sucA, sucB, hisJ, glnS, sucC, sucD, gltA, bioB, pheT, bioD, metK, sdhA, ybiC, tolB, ybiT, ldtB, moeA, gsiB, yliE, ihfA, serS, pflB, serC, aroA, ihfB, rpsA, mukE
16738553	Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi	2006-01-01	pmrR, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeB, yohO, arnE, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, wecF, yigE, blr, yggP, cpxP, hdfR, thiS, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, yhaM, tdcG, ytfR, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yneM, ykfM, ylcI, yciY, yncL, ylcH, ynhF, yciZ, ydgU, ypfM, ymgI, ymgJ, dinQ
16397293	Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner	2006-01-01	pmrR, yfaS, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeF, yoeB, yohO, arnE, ypdJ, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, yifN, wecF, yigE, blr, yggP, cpxP, ygaY, hdfR, thiS, yedN, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, glvC, yhaM, tdcG, ytfR, yehH, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, gapC, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, yedS, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yaiX, yoeA, yneM
16381862	MEROPS: the peptidase database. Nucleic Acids Res. Neil D Rawlings , Fraser R Morton , Alan J Barrett	2006-01-01	yghX, lspA, rseP, yafL, yafJ, mhpC, hypF, yahJ, frmB, codA, pepD, yfhR, yajL, clpP, lon, trpD, allB, allC, loiP, ompT, mepH, dacA, asnB, ybfF, nagA, dacC, iaaA, ddpX, ycaL, ycbK, ycbZ, hyaD, cohE, abgA, umuD, ldcA, pyrC, yfbL, sohB, puuD, abgB, mpaA, ynbC, ycjY, ydcP, pqqL, htpX, dcp, prc, pyrG, nlpC, sppA, tsaB, pepT, ptrB, mepM, ydgD, hchA, dacD, rutD, yegQ, pbpG, mepS, menH, elaD, purF, mepA, ypdE, ypdF, ampH, yfeW, nlpD, bepA, lepB, degP, iap, pepN, ptrA, guaA, ygeR, hyuA, ygeY, guaD, pepP, hycI, pppA, aes, tsaD, agaA, yhbO, ftsH, dacB, gltB, tldD, degQ, gspO, yheT, degS, pabA
15911532	Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol Cell Proteomics Ana Lopez-Campistrous , Paul Semchuk , Lorne Burke , Taunja Palmer-Stone , Stephen J Brokx , Gordon Broderick , Drell Bottorff , Sandra Bolch , Joel H Weiner , Michael J Ellison	2005-08-01	-
15357303	Factors influencing preferential utilization of RNA polymerase containing sigma-38 in stationary-phase gene expression in Escherichia coli. J. Microbiol. Eun Young Kim , Min-Sang Shin , Joon Haeng Rhee , Hyon E Choy	2004-06-01	lacZ, lacA, katE, bolA, rpoS, csgB, ssrS, hdeA, hdeB, pmbA, csgA, lacY
12029038	The highly conserved TldD and TldE proteins of Escherichia coli are involved in microcin B17 processing and in CcdA degradation. J Bacteriol Noureddine Allali , Hassan Afif , Martine Couturier , Laurence Van Melderen	2002-06-01	-

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