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948661 efp

948661

efp

protein chain elongation factor EF-P

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition protein chain elongation factor EF-P

研究结论

Date Results Publications
2018-09-08 10:23:00 The activity of EF-P is controlled by recognition elements in the tRNA D-arm. 27216360
2018-03-03 11:04:00 study of the spatial distribution and ribosome-binding dynamics of EF-P in live E. coli cells; EF-P binds to and unbinds from translating ribosomes during at least 25% of all elongation events; it may bind during every elongation cycle 28588135
2017-11-25 12:38:00 Binding of EF-P stabilizes the P-site tRNA, particularly via interactions between its modification and the CCA end, thereby enforcing an alternative conformation of the polyproline-containing nascent chain, which allows a favorable substrate geometry for peptide bond formation. 29100052
2017-06-24 10:12:00 In the absence of EF-P, the presence of Rho utilization (rut) sites led to an ~30-fold decrease in translation of polyproline-encoding mRNAs. 27624127
2015-11-07 10:18:00 These findings indicate that the ability of a given PPX motif to initiate an EF-P-alleviated stall is strongly influenced by its local context. 25144653

名称对应

Type IDs
Synonymous ECK4141
Gene
UniProtKB-ID: EFP_ECOLI
UniprotKB: P0A6N4
UniParc: UPI000003762D
EMBL: X61676, U00096, U14003, AP009048
EnsemblGenome: BAE78149, b4147
KO: eco:b4147, ecj:JW4107
Nucleutide sequences
EMBL-CDS: BAE78149.1, AAA97046.1, CAA43851.1, AAC77107.1
EnsemblGenome_TRS: AAC77107, BAE78149
Protein sequencees
EnsemblGenome_PRO: AAC77107, BAE78149
RefSeq: NP_418571.1
Others
UniRef100: UniRef100_A7ZV18
UniRef90: UniRef90_A7ZV18
UniRef50: UniRef50_P57133

全选

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研究热度

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