| Type | Description |
|---|---|
| Definition | DNA-binding transcriptional activator CadC |
| Date | Results | Publications |
|---|---|---|
| 2018-09-22 11:47:00 | Here, the authors present the crystal structure of the CadC DNA-binding domain (DBD) and show that it adopts a winged helix-turn-helix fold. | 28432336 |
| 2015-10-24 10:29:00 | The disordered CadC linker is required for transducing the pH-dependent response of the periplasmic sensor into a structural rearrangement that facilitates dimerization of the cytoplasmic CadC DNA-binding domain. | 25979249 |
| 2014-03-01 13:00:00 | Upon induction, lysine-dependent conformational changes in LysP transduce the lysine signal via a direct conformational coupling to CadC without resolving the interaction completely. | 24056175 |
| 2011-08-27 12:09:00 | Substitution of Cys208 and/or Cys272 by alanine resulted in CadC derivatives that were active in response to only one stimulus, either lysine or pH 5.8. | 21486484 |
| 2011-07-23 10:25:00 | Results describe the crystal structure of CadC(pd) (residues 188-512) solved at a resolution of 1.8 A via multiple wavelength anomalous dispersion (MAD) using a ReCl(6)(2-) derivative. | 21308846 |
| Type | IDs |
|---|---|
| Synonymous | ECK4127 |
| Gene |
UniProtKB-ID:
CADC_ECOLI
UniprotKB:
P23890
UniParc:
UPI0000126DA9
EMBL:
M67452,
U14003,
U00096,
AP009048
EnsemblGenome:
BAE78136,
b4133
KO:
eco:b4133,
ecj:JW4094
|
| Nucleutide sequences |
EMBL-CDS:
BAE78136.1,
AAA97033.1,
AAC77094.1,
AAA23531.1
EnsemblGenome_TRS:
AAC77094,
BAE78136
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC77094,
BAE78136
RefSeq:
NP_418557.1
|
| Others |
UniRef100:
UniRef100_P23890
UniRef90:
UniRef90_P23890
UniRef50:
UniRef50_P23890
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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