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948544 lexA

948544

lexA

DNA-binding transcriptional repressor LexA

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition DNA-binding transcriptional repressor LexA

研究结论

Date Results Publications
2021-01-16 15:54:00 Two components of DNA replication-dependent LexA cleavage. 32513870
2015-11-07 11:49:00 YbiB from Escherichia coli, the defining member of the novel Trpd2 family of prokaryotic DNA-binding proteins, forms an operon with the DNA helicase gene dinG and is under LexA control. 26063803
2013-07-06 10:38:00 Like the self-cleaving serine proteases LexA and UmuD in Escherichia coli, UmuDAb required RecA for cleavage. 22697494
2013-02-02 10:53:00 These results suggest that, IscR stabilizes LexA at the cka promoter after DNA damage thus, preventing its cleavage and inactivation, and this cooperation ensures that suicidal colicin K production is switched on only as a last resort. 22812562
2012-01-14 11:12:00 These results reveal specific amino acid determinants of the RecA-LexA interaction and suggest that LexA binds RecA and RecAi+6 at a composite site on the RecA filament, which could explain the role of the active filament during LexA cleavage. 21912525

名称对应

Type IDs
Synonymous ECK4035, exrA, spr, tsl, umuA
Gene
UniProtKB-ID: LEXA_ECOLI
UniprotKB: P0A7C2
UniParc: UPI0000042A94
EMBL: L02362, J01643, AP009048, U00006, U00096
EnsemblGenome: BAE78045, b4043
KO: ecj:JW4003, eco:b4043
Nucleutide sequences
EMBL-CDS: AAC77013.1, AAA24067.1, AAC43137.1, AAA24068.1, BAE78045.1
EnsemblGenome_TRS: AAC77013, BAE78045
Protein sequencees
EnsemblGenome_PRO: BAE78045, AAC77013
RefSeq: NP_418467.1
Others
UniRef100: UniRef100_A7ZUR5
UniRef90: UniRef90_A8AN85
UniRef50: UniRef50_A8AN85

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