| Type | Description |
|---|---|
| Definition | D-xylose:H(+) symporter |
| Date | Results | Publications |
|---|---|---|
| 2020-12-19 13:45:00 | Hydrogen-deuterium exchange mass spectrometry captures distinct dynamics upon substrate and inhibitor binding to a transporter. | 33268777 |
| 2017-11-26 00:38:00 | Molecular dynamics (MD) study of an all-atom model system to elucidate the atomistic details and the free-energy landscape along the path of binding a xylopyranose from the extracellular space to the inside of the transporter protein XylE. From the MD simulations, the Gibbs free energy of binding was found to be -4.4kcal/mol in agreement with the experimental value of -4.7kcal/mol. | 29032199 |
| 2017-08-19 10:42:00 | The models and subsequent experimental validation suggest that multiple residue substitutions are required to produce the thermodynamic and functional distinction between XylE and GLUT1. Despite the lack of simulation studies with substrates, these computational and biochemical characterizations provide unprecedented insight into the mechanistic difference between proton symporters and uniporters. | 28617850 |
| 2017-07-08 12:57:00 | studies suggest that a single carboxyl group in LacY (Glu325) may be the only side chain directly involved in H+ translocation and a carboxyl side chain with similar properties has been identified in FucP (Asp46) and XylE (Asp27), the present results imply that the pK of this residue is switched during H+/sugar symport in all three symporters. | 27227677 |
| 2015-12-19 10:31:00 | Studied conformational states and homology of LacY and XylE. | 25586173 |
| Type | IDs |
|---|---|
| Synonymous | ECK4023 |
| Gene |
UniProtKB-ID:
XYLE_ECOLI
UniprotKB:
P0AGF4
UniParc:
UPI000013905F
EMBL:
U00006,
AP009048,
U00096,
J02812,
X06663
EnsemblGenome:
BAE78033,
b4031
KO:
ecj:JW3991,
eco:b4031
|
| Nucleutide sequences |
EMBL-CDS:
AAC77001.1,
BAE78033.1,
AAC43125.1,
CAA29863.1,
AAA79016.1
EnsemblGenome_TRS:
BAE78033,
AAC77001
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE78033,
AAC77001
RefSeq:
NP_418455.1
|
| Others |
UniRef100:
UniRef100_P0AGF5
UniRef90:
UniRef90_P0AGF5
UniRef50:
UniRef50_P0AGF5
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员