rluF - 23S rRNA pseudouridine(2604) and tRNA(Tyr) pseudouridine(35) synthase-BMKCloudï½ç¾è¿å®¢äº

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948519 rluF

基因描述

Type	Description
Definition	23S rRNA pseudouridine(2604) and tRNA(Tyr) pseudouridine(35) synthase

研究结论

Date	Results	Publications
2017-05-27 11:59:00	Analysis of total tRNA isolated from E. coli pseudouridine synthase knock-out mutants identified RluF as the enzyme responsible for this modification.	27551044
2010-01-21 00:00:00	Results describe the crystal structure of an RluF-RNA complex, and suggest that a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome.	19298824

名称对应

Type	IDs
Synonymous	ECK4014, yjbC
Gene	UniProtKB-ID: RLUF_ECOLI UniprotKB: P32684 UniParc: UPI000013B51F EMBL: AP009048, U00006, U00096 EnsemblGenome: BAE78024, b4022 KO: ecj:JW3982, eco:b4022
Nucleutide sequences	EMBL-CDS: AAC76992.1, BAE78024.1, AAC43116.1 EnsemblGenome_TRS: BAE78024, AAC76992
Protein sequencees	EnsemblGenome_PRO: AAC76992, BAE78024 RefSeq: NP_418446.1
Others	UniRef100: UniRef100_P32684 UniRef90: UniRef90_P32684 UniRef50: UniRef50_P32684

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
27551044	Pseudouridine in the Anticodon of Escherichia coli tRNATyr(QÎ¨A) Is Catalyzed by the Dual Specificity Enzyme RluF. J Biol Chem Balasubrahmanyam Addepalli , Patrick A Limbach	2016-10-14	-
19298824	Crystal structure of an RluF-RNA complex: a base-pair rearrangement is the key to selectivity of RluF for U2604 of the ribosome. J Mol Biol Akram Alian , Andrew DeGiovanni , Sarah L Griner , Janet S Finer-Moore , Robert M Stroud	2009-05-15	-
18554609	An indigenous posttranscriptional modification in the ribosomal peptidyl transferase center confers resistance to an array of protein synthesis inhibitors. J. Mol. Biol. Seok-Ming Toh , Alexander S Mankin	2008-07-18	-
17668295	Insights into the biology of Escherichia coli through structural proteomics. J. Struct. Funct. Genomics Allan Matte , Zongchao Jia , S Sunita , J Sivaraman , Miroslaw Cygler	2007-09-01	-
17113994	Pseudouridine synthases. Chem. Biol. Tomoko Hamma , Adrian R FerrÃ©-D'AmarÃ©	2006-11-01	rsuA, rluC, rluE, rluB, rluA, truA, rluD, truD, truC, truB, rluF
16712869	Domain organization and crystal structure of the catalytic domain of E.coli RluF, a pseudouridine synthase that acts on 23S rRNA. J. Mol. Biol. S Sunita , H Zhenxing , J Swaathi , Miroslaw Cygler , Allan Matte , J Sivaraman	2006-06-16	rluF
16738553	Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi	2006-01-01	pmrR, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeB, yohO, arnE, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, wecF, yigE, blr, yggP, cpxP, hdfR, thiS, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, yhaM, tdcG, ytfR, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yneM, ykfM, ylcI, yciY, yncL, ylcH, ynhF, yciZ, ydgU, ypfM, ymgI, ymgJ, dinQ
16397293	Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner	2006-01-01	pmrR, yfaS, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeF, yoeB, yohO, arnE, ypdJ, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, yifN, wecF, yigE, blr, yggP, cpxP, ygaY, hdfR, thiS, yedN, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, glvC, yhaM, tdcG, ytfR, yehH, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, gapC, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, yedS, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yaiX, yoeA, yneM
11917006	Comparative genomics and evolution of proteins involved in RNA metabolism. Nucleic Acids Res. Vivek Anantharaman , Eugene V Koonin , L Aravind	2002-04-01	-
11720289	Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli. RNA M Del Campo , Y Kaya , J Ofengand	2001-11-01	yqcB, rrlH, rluE, rluB, truC, rrlG, rrlD, rrlC, rrlB, rrlE, rluF

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