| Type | Description |
|---|---|
| Definition | zinc responsive, periplasmic protein with chaperone activity |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | A structure-function study of ZraP and ZraS provides new insights into the two-component system Zra. | 33309686 |
| 2020-03-21 12:09:00 | Deletion of the ZraP coding gene from the E. coli genome resulted in a phenotype with tolerance to very high zinc concentrations (up to 2.5mM) that were lethal to wild type E. coli. These results exclude a direct role for ZraP in Zn(2+) tolerance in E. coli. | 30616070 |
| 2019-09-28 12:37:00 | Study shows that the deletion of zraP or zraR confers increased susceptibility to five classes of antibiotics and to some environmental stress targeting the envelope. A microscopy approach establishes that ZraP and ZraR are required to maintain envelope integrity. ZraP protects the cell from envelope stress via its inhibitory function of the system. | 30389436 |
| 2012-03-10 10:24:00 | zraP has a role in zinc adsorption and can be used for bioremediation | 21674266 |
| 2007-11-05 21:38:00 | N-terminus verified by Edman degradation on mature peptide | 9694902 |
| Type | IDs |
|---|---|
| Synonymous | ECK3994, yjaI, zra |
| Gene |
UniProtKB-ID:
ZRAP_ECOLI
UniprotKB:
P0AAA9
UniParc:
UPI000013C474
EMBL:
AP009048,
U00006,
U00096
EnsemblGenome:
b4002,
BAE77317
KO:
ecj:JW5546,
eco:b4002
|
| Nucleutide sequences |
EMBL-CDS:
BAE77317.1,
AAC43100.1,
AAC76976.2
EnsemblGenome_TRS:
AAC76976,
BAE77317
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC76976,
BAE77317
RefSeq:
NP_418430.2
|
| Others |
UniRef100:
UniRef100_P0AAB0
UniRef90:
UniRef90_Q8CVI9
UniRef50:
UniRef50_Q8CVI9
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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