| Type | Description |
|---|---|
| Definition | zinc responsive, periplasmic protein with chaperone activity |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | A structure-function study of ZraP and ZraS provides new insights into the two-component system Zra. | 33309686 |
| 2020-03-21 12:09:00 | Deletion of the ZraP coding gene from the E. coli genome resulted in a phenotype with tolerance to very high zinc concentrations (up to 2.5mM) that were lethal to wild type E. coli. These results exclude a direct role for ZraP in Zn(2+) tolerance in E. coli. | 30616070 |
| 2019-09-28 12:37:00 | Study shows that the deletion of zraP or zraR confers increased susceptibility to five classes of antibiotics and to some environmental stress targeting the envelope. A microscopy approach establishes that ZraP and ZraR are required to maintain envelope integrity. ZraP protects the cell from envelope stress via its inhibitory function of the system. | 30389436 |
| 2012-03-10 10:24:00 | zraP has a role in zinc adsorption and can be used for bioremediation | 21674266 |
| 2007-11-05 21:38:00 | N-terminus verified by Edman degradation on mature peptide | 9694902 |
| Type | IDs |
|---|---|
| Synonymous | ECK3994, yjaI, zra |
| Gene |
UniProtKB-ID:
ZRAP_ECOLI
UniprotKB:
P0AAA9
UniParc:
UPI000013C474
EMBL:
AP009048,
U00006,
U00096
EnsemblGenome:
b4002,
BAE77317
KO:
ecj:JW5546,
eco:b4002
|
| Nucleutide sequences |
EMBL-CDS:
BAE77317.1,
AAC43100.1,
AAC76976.2
EnsemblGenome_TRS:
AAC76976,
BAE77317
|
| Protein sequencees |
EnsemblGenome_PRO:
AAC76976,
BAE77317
RefSeq:
NP_418430.2
|
| Others |
UniRef100:
UniRef100_P0AAB0
UniRef90:
UniRef90_Q8CVI9
UniRef50:
UniRef50_Q8CVI9
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
Institut de Biologie Structurale |
2 |
| 2 |
Delft University of Technology |
2 |
| 3 |
University of Wisconsin-Madison |
1 |
| 4 |
Josephine Bay Paul Center, Marine Biological Laboratory, Woods Hole, MA 02543, USA. mriley@mbl.edu |
1 |
| 5 |
University of Wisconsin |
1 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
V Burland |
2 |
| 2 |
G Plunkett |
2 |
| 3 |
F R Blattner |
2 |
| 4 |
Takashi Horiuchi |
2 |
| 5 |
Hirotada Mori |
2 |