例如:"NBL1", "4681", "drought"
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948488 rpoB

948488

rpoB

RNA polymerase subunit beta

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition RNA polymerase subunit beta

研究结论

Date Results Publications
2018-01-06 12:08:00 The C-terminal segment of coliphage HK022 Nun interacts with the RNA polymerase beta and beta' subunits inside the RNA polymerase active site cleft as well as with nearly every element of the nucleic acid scaffold, essentially crosslinking the RNA polymerase and the nucleic acids to prevent translocation. 28318486
2017-12-02 11:15:00 Overexpression of recombinant inhibitor of host bacterial RNA polymerase (Gp2) in exponentially growing E. coli induces changes in RNAP behavior at single molecule level and induces global alterations in the transcriptional programme. 28977482
2017-12-02 11:10:00 The properties of generated RNA polymerase (RNAP) beta subunit variants Iindicate an RNA/protein interaction network that is crucial for transcription, thereby explaining the details of initiation-to-elongation transition on atomic level. 29036608
2017-08-26 10:29:00 ppGpp binds to two distinct sites 60 A apart on E. coli RNA polymerase (RNAP), one characterized previously (site 1) and a second identified here at an interface of RNAP and the transcription factor DksA (site 2). Site 2 binding results in the majority of ppGpp's effects on transcription initiation in vitro and in vivo, and strains lacking site 2 are severely impaired for growth following nutritional shifts. 27237053
2017-07-08 13:19:00 The D654Y single amino acid substitution in RpoB rendered E. coli cells resistant to osmotic stress, probably due to improved cell growth and viability via enhanced sugar uptake under stressed conditions, and activated a potential "pre-defense" mechanism under non-stressed conditions. The findings of this work will be useful for bacterial host improvement to enhance its resistance to osmotic stress and facilitate bio-base 28193207

名称对应

Type IDs
Synonymous ECK3978, ftsR, groN, nitB, rif, ron, sdgB, stl, stv, tabD
Gene
UniProtKB-ID: RPOB_ECOLI
UniprotKB: P0A8V2
UniParc: UPI000011F6D8
EMBL: U00006, M38292, AP009048, M38303, M38287, U76222, M38293, U00096, U77436, V00339, M38304, V00340, V00341
EnsemblGenome: BAE77333, b3987
KO: ecj:JW3950, eco:b3987
Nucleutide sequences
EMBL-CDS: AAA24579.1, AAC43085.1, AAA24585.1, AAD09605.1, CAA23625.1, BAE77333.1, CAA23627.1, AAC76961.1, AAB18647.1, CAA23629.1, AAA24580.1, AAA24583.1, AAA24581.1
EnsemblGenome_TRS: BAE77333, AAC76961
Protein sequencees
EnsemblGenome_PRO: BAE77333, AAC76961
RefSeq: NP_418414.1
Others
UniRef100: UniRef100_A7ZUK1
UniRef90: UniRef90_A7ZUK1
UniRef50: UniRef50_P06173

全选

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