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948482 tufB

948482

tufB

translation elongation factor Tu 2

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition translation elongation factor Tu 2

研究结论

Date Results Publications
2017-06-03 12:18:00 we engineered an approximately 700-million-year-old inferred ancestral variant of tufB, an essential gene encoding elongation factor Tu, and inserted it in a modern Escherichia coli genome in place of the native tufB gene. We subsequently evolved replicate hybrid bacterial populations for 2000 generations and examined the adaptive response via fitness assays, whole genome sequencing, proteomics, and biochemical assays. 28233029
2014-11-22 13:36:00 Comparison of DeltaDeltaG(o) values for binding EF-Tu to aa-tRNA show that the majority of the interface residues stabilize the ternary complex and their thermodynamic contribution can depend on the tRNA species that is used. 25094027
2010-01-21 00:00:00 Ecdomains 2+3 suppressed the GTPase activity of the E coli domain 1, whereas those of Bacillut thuringensis EF-Tu stimulated the Bstdomain 1 GTPase. 16081328
2010-01-21 00:00:00 Fusidic acid increases traps the ribosome EF-G complex in a preexisting conformation formed during translation. Only the 0.3 state is observed when poly(Phe) synthesis is prevented by omission of EF-Tu. 17727272
2007-11-05 21:38:00 N-terminus verified by Edman degradation on mature peptide 6997043,7021545,9298646

名称对应

Type IDs
Synonymous ECK3971, kirT, pulT
Gene
UniProtKB-ID: EFTU2_ECOLI
UniprotKB: P0CE48
UniParc: UPI0000110FB2
EMBL: U00096, U00006, AP009048, X57091, J01717
EnsemblGenome: b3980, BAE77340
KO: eco:b3980, ecj:JW3943
Nucleutide sequences
EMBL-CDS: AAC43078.1, AAC76954.1, BAE77340.1, AAA24669.1, CAA40370.1
EnsemblGenome_TRS: AAC76954, BAE77340
Protein sequencees
EnsemblGenome_PRO: AAC76954, BAE77340
RefSeq: NP_418407.1
Others
UniRef100: UniRef100_P14647
UniRef90: UniRef90_P14647
UniRef50: UniRef50_P14647

全选

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