metF - 5,10-methylenetetrahydrofolate reductase-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

收藏

948432 metF

基因描述

Type	Description
Definition	5,10-methylenetetrahydrofolate reductase

研究结论

Date	Results	Publications
2010-01-21 00:00:00	Results suggest that Leu may be a suitable replacement for Phe223 in the oxidative half-reaction of E. coli methylenetetrahydrofolate reductase.	19610625
2010-01-21 00:00:00	Multiple onformation, which allows aspartic acid 120 to hydrogen bond to the pterin ring in the folate complex but must move to an "open" conformation to allow NADH to bind.	16114881
2010-01-21 00:00:00	The invariant aspartate 120 is a critical residue for E. coli methylenetetrahydrofolate reductase, with major roles in folate binding and catalysis, and a minor role in redox modulation.	15865426

名称对应

Type	IDs
Synonymous	ECK3933
Gene	UniProtKB-ID: METF_ECOLI UniprotKB: P0AEZ1 UniParc: UPI000012EF8B EMBL: L19201, V01502, U00096, AP009048 EnsemblGenome: b3941, BAE77369 KO: eco:b3941, ecj:JW3913
Nucleutide sequences	EMBL-CDS: BAE77369.1, AAC76923.1, CAA24747.1, AAB03073.1 EnsemblGenome_TRS: BAE77369, AAC76923
Protein sequencees	EnsemblGenome_PRO: BAE77369, AAC76923 RefSeq: NP_418376.1
Others	UniRef100: UniRef100_P0AEZ1 UniRef90: UniRef90_P0AEZ1 UniRef50: UniRef50_P0AEZ1

全选

{{proteinIndex+1}}

mRNA

Protein

UniprotKB

Description

Refseq

{{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}

Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location

( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

收藏到我的文献

全选

Pubmed编号	文献信息	发表日期	相关基因
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
19610625	Functional role for the conformationally mobile phenylalanine 223 in the reaction of methylenetetrahydrofolate reductase from Escherichia coli. Biochemistry Moon N Lee , Desire Takawira , Andriana P Nikolova , David P Ballou , Vivek C Furtado , Ngoc L Phung , Brady R Still , Melissa K Thorstad , John J Tanner , Elizabeth E Trimmer	2009-08-18	-
17366475	From the genome sequence to the proteome and back: evaluation of E. coli genome annotation with a 2-D gel-based proteomics approach. Proteomics Isabelle Maillet , Peter Berndt , CÃ©line Malo , Sabrina Rodriguez , RenÃ© A Brunisholz , Zoltan Pragai , Sabine Arnold , Hanno Langen , Markus Wyss	2007-04-01	yjjV, yigL, ispH, yddE, can, yadG, sufD, yjjJ, hscA, galM, panC, ybbA, allE, rsfS, nagA, bioA, ybiT, gsiB, nfsA, serS, cmk, mukF, ycfP, cobB, minE, dadX, narL, tdk, ribC, add, ydjA, maeA, frsA, rspR, kdgR, rnt, thrS, pheS, ycgL, yeaG, rlmA, yebE, cmoA, uvrY, fliM, ribE, hisA, hisH, hisC, pfo, udk, yegQ, gatA, yegW, fruB, bglX, yfbU, yfcH, prmB, glk, pdxK, yfgM, iscS, wbbI, rpoE, tyrA, nhoA, ygdG, rlmC, queF, lysA, ygfF, thiL, zapA, yggS, rcsB, yghU, yghA, leuS, ybiX, ebgR, srlQ, yqjG, pnp, speB, ptsN, yhbJ, tldD, yhdE, yrdA, acuI, yheS, yhhX, ugpQ, ybeZ, ghrB, avtA, gmk, yidR
17187058	Absolute protein expression profiling estimates the relative contributions of transcriptional and translational regulation. Nat. Biotechnol. Peng Lu , Christine Vogel , Rong Wang , Xin Yao , Edward M Marcotte	2007-01-01	sspA, talB, dnaK, dnaJ, rpsT, ileS, dapB, carB, ftsZ, murE, aceF, acpP, surA, secA, can, aceE, panB, argF, lpxA, dksA, lpd, erpA, skp, dapD, acnB, tsf, glnH, fabZ, metQ, accA, galM, sodB, panC, pyrH, codA, opgG, pepD, tauB, eno, proC, phoR, thiI, gpmA, leuC, tig, clpP, clpX, lon, adk, htpG, acrB, trpD, apt, ydgH, rplT, purK, ompT, thrC, ybeD, ahpC, purR, glf, serA, miaB, pgm, seqA, rfbB, iscR, asnB, mprA, fldA, fur, sucA, sucB, hisJ, glnS, sucC, sucD, gltA, bioB, pheT, bioD, metK, sdhA, ybiC, tolB, ybiT, ldtB, moeA, gsiB, yliE, ihfA, serS, pflB, serC, aroA, ihfB, rpsA, mukE
17012394	Experimental and computational assessment of conditionally essential genes in Escherichia coli. J. Bacteriol. Andrew R Joyce , Jennifer L Reed , Aprilfawn White , Robert Edwards , Andrei Osterman , Tomoya Baba , Hirotada Mori , Scott A Lesely , Bernhard Ã Palsson , Sanjay Agarwalla	2006-12-01	carB, leuB, cra, panB, pdxA, panC, proC, leuC, trpD, purK, fes, thrC, serA, gltA, nadA, trpC, serC, aroA, pyrD, leuD, panD, icd, trpB, cysB, pyrC, thrA, trpE, leuL, trpA, aroD, metC, pabB, proB, hisI, hisF, hisA, hisD, hisH, hisG, hisC, hisB, ubiG, proA, pdxB, purF, pdxH, aroC, cysK, ptsI, crr, cysU, cysP, cysA, purC, purM, guaB, iscS, glyA, purL, pdxJ, nadB, pheA, tyrA, pyrF, cysD, cysN, cysC, cysH, cysI, cysJ, argA, lysA, guaA, prfB, ubiH, leuA, thrB, folB, rpsU, folP, glmM, aroE, pabA, aroB, glpD, panM, cysE, pyrE, ilvB, atpA, atpG, atpC, atpF, atpB, atpH, ilvD, ilvC, ilvA, metR
16605249	Structural perturbations in the Ala --> Val polymorphism of methylenetetrahydrofolate reductase: how binding of folates may protect against inactivation. Biochemistry Robert Pejchal , Elizabeth Campbell , Brian D Guenther , Brett W Lennon , Rowena G Matthews , Martha L Ludwig	2006-04-18	-
16738553	Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110. Mol. Syst. Biol. Koji Hayashi , Naoki Morooka , Yoshihiro Yamamoto , Katsutoshi Fujita , Katsumi Isono , Sunju Choi , Eiichi Ohtsubo , Tomoya Baba , Barry L Wanner , Hirotada Mori , Takashi Horiuchi	2006-01-01	pmrR, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeB, yohO, arnE, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, wecF, yigE, blr, yggP, cpxP, hdfR, thiS, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, yhaM, tdcG, ytfR, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yneM, ykfM, ylcI, yciY, yncL, ylcH, ynhF, yciZ, ydgU, ypfM, ymgI, ymgJ, dinQ
16397293	Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. Monica Riley , Takashi Abe , Martha B Arnaud , Mary K B Berlyn , Frederick R Blattner , Roy R Chaudhuri , Jeremy D Glasner , Takashi Horiuchi , Ingrid M Keseler , Takehide Kosuge , Hirotada Mori , Nicole T Perna , Guy Plunkett , Kenneth E Rudd , Margrethe H Serres , Gavin H Thomas , Nicholas R Thomson , David Wishart , Barry L Wanner	2006-01-01	pmrR, yfaS, torI, yaeP, ykfH, ykgO, ylcG, rzoD, ybdZ, cydX, gnsA, insA, ymgF, ymiA, yciX, rzoR, ynfO, yniD, yobH, yoeF, yoeB, yohO, arnE, ypdJ, ypeB, ypfN, ypjJ, arfA, yheV, ysaB, sgcB, yjhX, ytjA, yibT, yicS, yidD, yifL, ghoT, yjjZ, mntS, iroK, yifN, wecF, yigE, blr, yggP, cpxP, ygaY, hdfR, thiS, yedN, greB, rtcA, smf, ygcU, ypjK, hokE, sslE, glcF, glcE, glvC, yhaM, tdcG, ytfR, yehH, hokB, ldrD, hokA, ldrA, ldrB, ecnA, ecnB, gapC, yfjD, yhdP, yjjV, cysW, hokC, ghxQ, tatD, yjdP, cutC, nirC, frlC, aroK, gntU, yedS, dgoD, dgoA, dgoR, yigL, ldrC, ylbE, ydbJ, yeiW, yehK, yaiX, yoeA, yneM
15961124	A bacterial model for studying effects of human mutations in vivo: Escherichia coli strains mimicking a common polymorphism in the human MTHFR gene. Mutat. Res. Joanna JakÃ³bkiewicz-Banecka , Anna Kloska , Magdalena Stepnowska , Bogdan Banecki , Alicja Wegrzyn , Grzegorz Wegrzyn	2005-10-15	metF, MTHFR
16114881	Structures of NADH and CH3-H4folate complexes of Escherichia coli methylenetetrahydrofolate reductase reveal a spartan strategy for a ping-pong reaction. Biochemistry Robert Pejchal , Ryan Sargeant , Martha L Ludwig	2005-08-30	metF

研究热度

热点单位

排名	科研单位	文献
{{affIndex+1}}	{{aff.value}}	{{aff.size}}

目前还没有研究热点单位

热点人员

排名	研究人员	文献
{{authorIndex+1}}	{{author.value}}	{{author.size}}

目前还没有研究热点人员

© 2017 biocloud.net版权所有 ICP证：京10042835号