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948353 dsbA

948353

dsbA

thiol:disulfide oxidoreductase DsbA

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition thiol:disulfide oxidoreductase DsbA

研究结论

Date Results Publications
2017-06-24 10:16:00 analysis of mutants that map to two areas in the structure of DsbB, one located between the two first transmembrane segments where the quinone ring binds and the other located in the second periplasmic loop of DsbB, which interacts with DsbA 28232484
2014-05-17 14:00:00 DsbA and DsbL introduce the disulfide bond into unfolded bacterial aryl sulfotransferase at similar rates. 24601529
2013-07-13 11:13:00 A high-resolution structural model of integral membrane protein DsbB in E. coli is responsible for oxidizing the periplasmic protein DsbA, which forms disulfide bonds in substrate proteins. 23416557
2010-10-04 12:02:00 Data found that the periplasmic disulfide isomerase DsbC cooperates with SurA and the thiol oxidase DsbA in the folding of the essential beta-barrel protein LptD. 20615876
2010-05-03 11:37:00 Studies indicate that DsbA could effectively assist proteins folding, both in vivo coexpressed with the target protein, and in vitro replenished as foldases. 17366881

名称对应

Type IDs
Synonymous ECK3852, dsf, iarA, ppfA
Gene
UniProtKB-ID: DSBA_ECOLI
UniprotKB: P0AEG4
UniParc: UPI000002D10B
EMBL: AP009048, U36835, U36829, X80762, U00096, U35821, U35819, U36834, U36831, U36830, U35662, L19201, U36833, X63186, U35825, U35823, M77746, U36828, U35817, U35820, U35822, U36832, U35824, U35818
EnsemblGenome: b3860, BAE77448
KO: eco:b3860, ecj:JW3832
Nucleutide sequences
EMBL-CDS: AAC43532.1, AAC43519.1, AAC76858.1, CAA44868.1, BAE77448.1, AAC43523.1, AAC43530.1, AAC43522.1, AAC43527.1, AAC43531.1, AAC43534.1, AAA82614.1, AAC43520.1, AAC43525.1, CAA56736.1, AAC43535.1, AAC43526.1, AAA23715.1, AAC43521.1, AAB02995.1, AAC43524.1, AAC43533.1, AAC43528.1, AAC43529.1
EnsemblGenome_TRS: AAC76858, BAE77448
Protein sequencees
EnsemblGenome_PRO: AAC76858, BAE77448
RefSeq: NP_418297.1
Others
UniRef100: UniRef100_P0AEG5
UniRef90: UniRef90_P52235
UniRef50: UniRef50_P52235

全选

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