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948327 rfaH

948327

rfaH

transcription antiterminator RfaH

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition transcription antiterminator RfaH

研究结论

Date Results Publications
2019-05-18 10:46:00 Strikingly, the non-template DNA forms a hairpin in the RfaH:ops complex structure, flipping out a conserved T residue that is specifically recognized by RfaH. Molecular modeling and genetic evidence support the notion that ops hairpin is required for RfaH recruitment. 29741479
2017-10-14 10:07:00 In contrast to NusG, which freely binds to RNA polymerase, RfaH exists in a structurally distinct autoinhibitory state in which the RNA polymerase-binding site is buried at the interface between two RfaH domains. 28605514
2016-05-21 12:04:00 The presence of the leucine-rich element in the RfaH C-terminal domain may be responsible for its flexible structural behavior. 25483894
2016-05-21 11:43:00 Data indicate that the RfaH transcriptional regulator protein beta-barrel conformation is much more stable than the alpha-helix conformation. 26033324
2015-04-25 12:31:00 The importance of interfacial interactions between the two domains of RfaH is highlighted by the compromised structural integrity of the helical form of the C-terminal doamin in the absence N-terminal domain. 24758259

名称对应

Type IDs
Synonymous ECK3834, hlyT, sfrB
Gene
UniProtKB-ID: RFAH_ECOLI
UniprotKB: P0AFW0
UniParc: UPI00001337B2
EMBL: X65013, M94889, M87049, AP009048, U00096
EnsemblGenome: b3842, BAE77461
KO: eco:b3842, ecj:JW3818
Nucleutide sequences
EMBL-CDS: AAA91060.1, AAA67638.1, AAC76845.1, CAA46147.1, BAE77461.1
EnsemblGenome_TRS: AAC76845, BAE77461
Protein sequencees
EnsemblGenome_PRO: AAC76845, BAE77461
RefSeq: NP_418284.1
Others
UniRef100: UniRef100_P0AFW1
UniRef90: UniRef90_Q0TAL4
UniRef50: UniRef50_Q0TAL4

全选

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研究热度

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