| Type | Description |
|---|---|
| Definition | ATP-dependent DNA helicase RecQ |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:35:00 | The HRDC domain oppositely modulates the unwinding activity of E. coli RecQ helicase on duplex DNA and G-quadruplex. | 33454004 |
| 2019-08-24 11:47:00 | This study shows that replication fork regression, the combination of replication fork reversal leading to formation of a Holliday Junction along with exonuclease digestion, is the preferred pathway for dealing with a collapsed fork in Escherichia coli. The protein that had the greatest effect on these fork processing events was the RecQ helicase. | 30466158 |
| 2019-07-13 10:59:00 | RecQ operated under 2 interconvertible kinetic modes, 'slow' and 'normal', as it unwound duplex DNA and translocated on single-stranded (ss) DNA. Abasic sites blocked RecQ unwinding. Removal of the HRDC domain eliminates only the slow mode. A RecQ variant lacking both the WH and HRDC domains retains weak helicase activity. | 30053104 |
| 2018-01-20 12:06:00 | To illustrate the single-molecule unwinding assay and the analysis routine, we provide DNA unwinding measurements of Escherichia coli RecQ helicase under a variety of conditions (Na+, ATP, temperature, and DNA substrate geometry). | 27131595 |
| 2017-12-30 12:36:00 | Coupling of helicase and RecA-loading activity during dsDNA-end resection is crucial in avoiding the deleterious effects of a long and stabile 3' tail in E. coli. | 28689072 |
| Type | IDs |
|---|---|
| Synonymous | ECK3816 |
| Gene |
UniProtKB-ID:
RECQ_ECOLI
UniprotKB:
P15043
UniParc:
UPI00003B260D
EMBL:
AP009048,
U00096,
M87049,
M30198
EnsemblGenome:
b3822,
BAE77479
KO:
ecj:JW5855,
eco:b3822
|
| Nucleutide sequences |
EMBL-CDS:
AAT48221.1,
BAE77479.1,
AAA67618.1,
AAA24517.1
EnsemblGenome_TRS:
AAT48221,
BAE77479
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE77479,
AAT48221
RefSeq:
YP_026263.3
|
| Others |
UniRef100:
UniRef100_P15043
UniRef90:
UniRef90_P15043
UniRef50:
UniRef50_P15043
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员