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948158 slmA

948158

slmA

nucleoid occlusion factor SlmA

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition nucleoid occlusion factor SlmA

研究结论

Date Results Publications
2019-08-17 10:51:00 Here, we demonstrate that FtsZ can form crowding-induced condensates, reminiscent of those observed for eukaryotic proteins. Formation of these FtsZ-rich droplets occurs when FtsZ is bound to SlmA, a spatial regulator of FtsZ that antagonizes polymerization, while also binding to specific sites on chromosomal DNA. 30523075
2016-12-17 10:06:00 Combined, these data reveal the molecular basis for the SlmA-DNA-FtsZ interaction with implications for SlmA's NO function and underscore the ability of the FtsZ CTD to adopt a wide range of conformations, explaining its ability to bind diverse regulatory proteins. 27091999
2015-11-21 11:09:00 even in the absence of Min, SlmA, and the putative Ter macrodomain - Z-ring link, there remains a weak midcell positioning bias for the Z-ring. 25101671
2015-02-14 10:57:00 these results lead to a model in which SlmA binding to an SBS is activated to bind the tail of FtsZ resulting in further interaction with FtsZ leading to depolymerization of FtsZ polymers. 25078077
2013-09-07 11:56:00 Structures show that SlmA dramatically distorts DNA, allowing it to bind as an orientated dimer-of-dimers. Biochemical data indicate that SlmA dimer-of-dimers can spread along the DNA. 23754405

名称对应

Type IDs
Synonymous ECK3631, ttk, yicB
Gene
UniProtKB-ID: SLMA_ECOLI
UniprotKB: P0C093
UniParc: UPI00001377A3
EMBL: V01578, U00096, V01498, AP009048, L10328, X01714
EnsemblGenome: b3641, BAE77651
KO: ecj:JW5641, eco:b3641
Nucleutide sequences
EMBL-CDS: AAA61994.1, BAE77651.1, AAC76665.2, CAA25860.1, CAA24898.1
EnsemblGenome_TRS: BAE77651, AAC76665
Protein sequencees
EnsemblGenome_PRO: BAE77651, AAC76665
RefSeq: NP_418098.4
Others
UniRef100: UniRef100_A7ZTJ2
UniRef90: UniRef90_A6TFN2
UniRef50: UniRef50_Q9KVD2

全选

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