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948026 hdeB

948026

hdeB

periplasmic acid stress chaperone

protein-coding

Escherichia coli str. K-12 substr. MG1655

基因描述

Type Description
Definition periplasmic acid stress chaperone

研究结论

Date Results Publications
2016-09-24 10:52:00 HdeB activation is coupled to its intrinsic dynamics instead of structural changes, and therefore its functional mechanism is apparently different from HdeA. 26593705
2015-12-05 11:26:00 Of these proteins, only HdeB has convincingly been previously shown to function as chaperone in vivo. 26003922
2012-05-05 11:17:00 The authors conclude that E. coli O157:H7 strains have evolved acid survival strategies independent of the HdeA/B chaperones and are more acid resistant than nonpathogenic K-12. 22179243
2012-03-03 11:15:00 This analysis identifies a structural interaction within the HdeB monomer that is disrupted as pH is lowered, leading to enhanced structural flexibility. 22138344
2010-01-21 00:00:00 HdeA and HdeB not only help to maintain proteins in a soluble state during acid treatment, as previously reported, but also assist, both in vitro and in vivo, in the solubilization at neutral pH of mixed protein-chaperone aggregates formed at acidic pH 18359765

名称对应

Type IDs
Synonymous ECK3493, yhhD, yhiC
Gene
UniProtKB-ID: HDEB_ECOLI
UniprotKB: P0AET2
UniParc: UPI000012C3B9
EMBL: U00039, D11109, AP009048, U00096
EnsemblGenome: BAE77785, b3509
KO: ecj:JW5669, eco:b3509
Nucleutide sequences
EMBL-CDS: AAC76534.2, BAA01884.1, AAB18485.1, BAE77785.1
EnsemblGenome_TRS: AAC76534, BAE77785
Protein sequencees
EnsemblGenome_PRO: AAC76534, BAE77785
RefSeq: NP_417966.4
Others
UniRef100: UniRef100_P0AET3
UniRef90: UniRef90_P0AET3
UniRef50: UniRef50_P0AET3

全选

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