| Type | Description |
|---|---|
| Definition | DNA-binding transcriptional repressor NikR |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 11:00:00 | Both the Z(eff) of the metal ion and the donor nature of the ligands determine the electronic structure of the metal site metalloregulator NikR. This impacts the geometric structure of the metal site and thus the conformation of the protein. | 31339709 |
| 2010-11-06 10:46:00 | Structural basis of low-affinity nickel binding to the nickel-responsive transcription factor NikR from Escherichia coli | 20704276 |
| 2010-09-13 12:16:00 | localized this Ni(II) site to a region at the interface between the metal- and DNA-binding domains and identified His48 and His110 as residues that participate in the low-affinity Ni(II)-binding response | 20583753 |
| 2010-03-15 11:55:00 | Mutagenesis and cation exchange experiments reveal that K(+) is a critical structural component for the activation of Ni(II)-responsive DNA binding by NikR. | 20088519 |
| 2010-01-21 00:00:00 | Two crystal structures of nickel-activated E. coli NikR were reported. | 16945905 |
| Type | IDs |
|---|---|
| Synonymous | ECK3465, yhhG |
| Gene |
UniProtKB-ID:
NIKR_ECOLI
UniprotKB:
P0A6Z6
UniParc:
UPI0000130181
EMBL:
U00096,
L02370,
AP009048,
Y08952,
D21140,
U00039
EnsemblGenome:
BAE77812,
b3481
KO:
eco:b3481,
ecj:JW3446
|
| Nucleutide sequences |
EMBL-CDS:
AAC76506.1,
CAA70150.1,
BAA04676.1,
BAE77812.1,
AAC61882.1,
AAB18456.1
EnsemblGenome_TRS:
BAE77812,
AAC76506
|
| Protein sequencees |
EnsemblGenome_PRO:
BAE77812,
AAC76506
RefSeq:
NP_417938.1
|
| Others |
UniRef100:
UniRef100_A7ZT19
UniRef90:
UniRef90_A7ZT19
UniRef50:
UniRef50_A7ZT19
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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