| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase 8 interacting protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-02 12:06:00 | extensive biochemical characterization of the KLC:JIP1 interaction, as well as identification of potential KLC1-binding partners, improves the understanding of how this growing family of cargos is recruited to kinesin1 by KLC1. | 30026235 |
| 2017-06-24 10:40:00 | All binary complexes (KLC1:APP, KLC1:JIP1, and APP:JIP1) contain conformations with favorable binding free energies indicating that KLC1 and JIP1 may take part in APP transport in Alzheimer's disease patients. | 27891669 |
| 2014-06-07 10:23:00 | analysis of the role of JIP1 in APP transport; knockdown of JIP1 did not affect either amyloid precursor protein transport or amyloid-beta peptide production | 23825109 |
| 2013-11-16 11:12:00 | Data show that small GTPase RALA regulates formation of a JIP1 (C-Jun-amino-terminal-interacting protein 1) scaffold complex to propagate JNK signaling toward FOXO4 (forkhead box O transcription factor) in response to reactive oxygen species | 23770673 |
| 2013-08-03 11:35:00 | In resected pancreatic cancer, carriers of a minor allele for rs3824872 (MAPK8IP1) were associated with a survival advantage compared with noncarriers with an additional 2-year survival if both minor alleles were present. | 23360921 |
| Type | IDs |
|---|---|
| Synonymous | IB1, JIP-1, JIP1, PRKM8IP |
| Gene |
UniProtKB-ID:
JIP1_HUMAN,
Q6NUQ9_HUMAN
UniprotKB:
Q9UQF2,
Q6NUQ9
UniParc:
UPI0000352C0F,
UPI000003046D
EMBL:
AF007134,
BC068470,
AF074091,
CH471064
Ensembl:
ENSG00000121653
KO:
hsa:9479
|
| Nucleutide sequences |
EMBL-CDS:
EAW68027.1,
AAC19150.1,
AAD20443.1,
EAW68028.1,
AAH68470.1
Ensembl_TRS:
ENST00000241014
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000241014
RefSeq:
NP_005447.1
|
| Others |
UniRef100:
UniRef100_Q9UQF2,
UniRef100_Q6NUQ9
UniRef90:
UniRef90_Q9UQF2
UniRef50:
UniRef50_Q9UQF2
UniGene:
Hs.234249
CCDS:
CCDS7916.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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